STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccnd3Cyclin D3; Belongs to the cyclin family. (218 aa)    
Predicted Functional Partners:
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.978
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.974
rb1
Retinoblastoma 1.
    
 0.969
rbl1
Retinoblastoma-like 1 (p107).
    
 0.969
LOC108241005
Cyclin-dependent kinase inhibitor 1D.
   
 0.957
LOC112450491
Cyclin-dependent kinase inhibitor 1A.
   
 0.957
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.942
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.928
cdkn2d
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4).
    
 0.920
LOC108240964
Uncharacterized protein.
   
 0.852
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.