Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A1P8API0Transmembrane protein. (158 aa)    
Predicted Functional Partners:
HCC2
Protein SCO1 homolog 2, mitochondrial; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX (By similarity). Participates in copper and redox homeostasis; Belongs to the SCO1/2 family.
   
 0.861
HCC1
Protein SCO1 homolog 1, mitochondrial; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX. Plays an essential role in embryo development. Belongs to the SCO1/2 family.
   
 0.861
MIA40
Mitochondrial intermembrane space import and assembly protein 40 homolog; Required for the import and folding of small cysteine- containing proteins in the mitochondrial intermembrane space (Probable). Involved in the mitochondrial oxidative folding of the copper-zinc superoxide dismutase CSD1, the copper chaperone for superoxide dismutase CCS, and subunits of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in the peroxisomal oxidative folding of the copper-zinc superoxide dismutase CSD3, and the fatty acid beta-oxidation multifunctional protein AIM1.
   
 0.829
A0A178W5Y7
Transmembrane protein.
      
 0.826
K21L13.9
Transmembrane protein.
      
 0.826
A0A1P8B684
Transmembrane protein.
      
 0.823
YUP8H12R.22
Transmembrane protein.
      
 0.821
K20I9.2
Probable protein phosphatase 2C 41.
      
 0.819
F1N13.200
COX assembly mitochondrial protein.
   
 
 0.782
F9G14.70
Probable protein phosphatase 2C 67.
      
 0.778
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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