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TIC110 protein (Arabidopsis thaliana) - STRING interaction network
"TIC110" - Translocon at the inner envelope membrane of chloroplasts 110 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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TIC110Translocon at the inner envelope membrane of chloroplasts 110; Involved in protein precursor import into chloroplasts. Forms a voltage-dependent cation-selective channel at the inner envelope of chloroplasts, which specifically responds to a transit peptide. Associates with both the precursor and mature forms of the preprotein (1016 aa)    
Predicted Functional Partners:
TIC40
Chloroplast protein import (Tic40); Involved in protein precursor import into chloroplasts. Part of the motor complex consisting of a co-chaperone (TIC40) and a chaperone (HSP93) associated with the import channel (TIC110). Causes the release of bound transit peptides from TIC110 and stimulates ATP hydrolysis by HSP93. Involved in reinsertion of proteins from the chloroplast stroma into the inner membrane (447 aa)
     
  0.999
TOC159
Translocase of chloroplast 159; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Required for chloroplast biogenesis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast (1503 aa)
     
 
  0.994
CLPC1
CLPC homologue 1; Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus. May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma. May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b. Involved in leaf iron homeostasis (929 aa)
     
 
  0.986
TOC33
Translocase of chloroplast 33; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Binds GTP, GDP, XTP, but not ATP. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast, especially during early development stages (297 aa)
     
 
  0.980
TOC132
Translocase of chloroplast 132; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast (1206 aa)
     
 
  0.967
Tic32-IVa
NAD(P)-binding Rossmann-fold superfamily protein; Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32, TIC 55 and TIC62 (322 aa)
       
 
  0.965
TOC120
Translocase of chloroplast 120; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast (1089 aa)
       
 
  0.962
Tic20-I
Translocon at the inner envelope membrane of chloroplasts 20; Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope. Seems to be specific for photosynthesis-related pre-proteins. Partially redundant with TIC20-IV, but not with TIC20-II or TIC20-V (274 aa)
     
   
  0.960
TIC
TIME FOR COFFEE; Regulator of normal clock function. Acts in the mid to late night. Contributes to the amplitude of circadian clocks. May act on the transcriptional induction of LATE ELONGATED HYPOCOTYL (LHY). Inhibits MYC2 protein accumulation, acting as a negative factor in the JA-signaling pathway (1555 aa)
           
  0.959
TOC34
Translocase of chloroplast 34; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast (313 aa)
           
  0.958
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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