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TIL1 protein (Arabidopsis thaliana) - STRING interaction network
"TIL1" - TILTED 1 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIL1TILTED 1; DNA polymerase II participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions. Involved in maintaining epigenetic states, controlling hypersensitive response (HR), and mediating abscisic acid (ABA) signaling. Required for flowering repression through a mechanism involving epigenetic gene silencing. May participate in processes involved in chromatin-mediated cell [...] (2161 aa)    
Predicted Functional Partners:
ICU2
INCURVATA2; Polymerase alpha in a complex with DNA primase is a replicative polymerase (1524 aa)
     
  0.999
DPB2
DNA polymerase epsilon subunit B2; Participates in DNA repair and in chromosomal DNA replication (526 aa)
     
  0.999
MCM4
MINICHROMOSOME MAINTENANCE 4; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (847 aa)
     
  0.999
POLA2
DNA polymerase alpha 2; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (620 aa)
     
  0.998
POLA3
DNA primase small subunit (451 aa)
     
  0.998
MCM5
MINICHROMOSOME MAINTENANCE 5; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (727 aa)
     
  0.997
NF-YB11
Nuclear factor Y, subunit B11 (275 aa)
     
  0.997
MCM3
MINICHROMOSOME MAINTENANCE 3; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (776 aa)
     
  0.996
PRL
PROLIFERA; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (By similarity). Required for megagametophyte and embryo development (716 aa)
     
  0.996
EMB2780
DNA polymerase delta subunit 1; This polymerase possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3’- to 5’-direction (1112 aa)
     
  0.995
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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