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FATB protein (Arabidopsis thaliana) - STRING interaction network
"FATB" - Fatty acyl-ACP thioesterases B in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FATBFatty acyl-ACP thioesterases B; Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for palmitoyl-ACP versus other acyl-ACPs. Substrate preference is 16-0 > 18-1 > 18-0 > 16-1. Plays an essential role in the supply of saturated fatty acids necessary for plant growth and seed development. Contributes to 16-0 production particularly in flowers. May be involved in the synthesis of long chain fatty acid (412 aa)    
Predicted Functional Partners:
AT2G04540
Beta-ketoacyl synthase; Catalyzes all the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Able to elongate saturated acyl chains from 4 to at least 16 carbons. Uses malonyl-CoA but not acetyl-CoA as primer substrate. When expressed in a heterologous system, reveals a bimodal distribution of products, with peaks at C8 and C14-C16. The major product of the reaction (octanoyl-ACP) is required for the lipoylation of essential mitochondrial proteins (461 aa)
         
  0.984
KASI
3-ketoacyl-acyl carrier protein synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity) (489 aa)
         
  0.977
MOD1
MOSAIC DEATH 1; Catalyzes the NAD-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Catalyzes the last reduction step in the de novo synthesis cycle of fatty acids. Involved in the elongation cycle of fatty acids which are used in lipid metabolism. Required for normal plant growth (390 aa)
         
  0.971
SSI2
Suppressor of SA insensitive 2; Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain. Required for the activation of certain jasmonic acid (JA)-mediated responses and the repression of the salicylic acid (SA) signaling pathway (401 aa)
         
  0.965
LACS9
Long chain acyl-CoA synthetase 9; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate (691 aa)
         
  0.962
LACS8
Putative AMP-binding protein; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate (720 aa)
         
  0.961
AAE16
Acyl activating enzyme 16; May be involved in the activation of fatty acids to acyl-carrier-protein (722 aa)
         
  0.961
AAE15
Acyl-activating enzyme 15; Probably involved in the activation of fatty acids to acyl-carrier-protein prior to fatty acid elongation in plastids. Acts on medium- to long-chain fatty acids (727 aa)
         
  0.958
FAB1
Fatty acid biosynthesis 1; Essential protein that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-16 and C-16 to unsaturated C-18 fatty acids. Confers resistance to low temperatures by maintaining chloroplast membranes integrity. Involved in the regulation of fatty acids ratios during seed metabolism. Required for embryo development, especially at the transition from the globular to the heart stage (541 aa)
         
  0.953
FTM1
FLORAL TRANSITION AT THE MERISTEM1; Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain (391 aa)
         
  0.932
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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