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Z-ISO protein (Arabidopsis thaliana) - STRING interaction network
"Z-ISO" - 15-cis-zeta-carotene isomerase in Arabidopsis thaliana
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Predicted Interactions
gene neighborhood
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textmining
co-expression
protein homology
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Z-ISO15-cis-zeta-carotene isomerase; Isomerase involved in the biosynthesis of carotenoids. Catalyzes the cis- to trans-conversion of the 15-cis-bond in 9,15,9’-tri-cis-zeta-carotene (367 aa)    
Predicted Functional Partners:
ZDS
Zeta-carotene desaturase; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7’. Shows stereoselectivity toward trans C15- C15’zeta-carotene double bond. The zeta-carotene produced by the phytoene desaturase PDS has a C15-C15’ double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS. The main product is 7,9,7’,9’- tetra-cis-lycopene (pro-lycopene) (558 aa)
   
 
  0.998
PDS3
Phytoene desaturase 3; This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11’ positions of phytoene. The zeta-carotene produced has a central C15-C15’ double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS, the next enzyme in the lycopene biosynthesis pathway (566 aa)
   
 
  0.996
CRTISO
Carotenoid isomerase; Carotene cis-trans-isomerase that converts 7,9,9’-tri- cis-neurosporene to 9’-cis-neurosporene and 7,9,9’,7’-tetra-cis- lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis-double bonds at C9 and C9’. Carotenoid biosynthesis is partly required to form the prolamellar bodies [...] (595 aa)
     
 
  0.978
PSY
PHYTOENE SYNTHASE; Catalyzes the reaction from prephytoene diphosphate to phytoene (437 aa)
     
   
  0.874
AT2G29995
Tyrosine-sulfated glycopeptide 3; Promotes cellular proliferation and expansion (71 aa)
           
  0.862
LYC
Lycopene cyclase; Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene (501 aa)
           
  0.861
CCD1
Carotenoid cleavage dioxygenase 1; Cleaves a variety of carotenoids symmetrically at both the 9-10 and 9’-10’ double bonds. Active on beta,beta-carotene, lutein, zeaxanthin, all-trans-violaxanthin, 9-cis-violaxanthin and 9’-cis-neoxanthin. With most substrates, the carotenoid is symmetrically cleaved. Probably not involved in abscisic acid biosynthesis (538 aa)
     
   
  0.848
AT3G47295
Tyrosine-sulfated glycopeptide 2; Promotes cellular proliferation and expansion (71 aa)
           
  0.809
LUT2
LUTEIN DEFICIENT 2; Catalyzes the single epsilon-cyclization reaction which converts lycopene to delta-carotene and neurosporene to alpha- zeacarotene. Required for lutein biosynthesis (524 aa)
     
   
  0.807
CYP97A3
Cytochrome P450, family 97, subfamily A, polypeptide 3; Heme-containing cytochrome P450 involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylation of alpha- and beta-carotene. Has also a low activity toward the epsilon-rings of alpha-carotene. The beta-ring of alpha-carotene is the preferred substrate in planta (595 aa)
     
   
  0.806
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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