STRINGSTRING
UTR3 protein (Arabidopsis thaliana) - STRING interaction network
"UTR3" - UDP-galactose/UDP-glucose transporter 3 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UTR3UDP-galactose/UDP-glucose transporter 3; Essential sugar transporter required for the transport of UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum. Essential for pollen development and involved in embryo sac progress; Belongs to the nucleotide-sugar transporter family. UDP-galactose-UMP antiporter (TC 2.A.7.11) subfamily (331 aa)    
Predicted Functional Partners:
ATERDJ3B
DNAJ heat shock family protein; J domain protein localized in ER lumen. Can partially compensate for the growth defect in jem1 scj1 mutant yeast. Forms a complex SDF2-ERdj3B-BiP that is required for the proper accumulation of the surface-exposed leucine-rich repeat receptor kinases EFR. EFR is involved in PAMP (pathogen associated molecular patterns) triggered immunity (346 aa)
     
        0.982
AT4G16660
Heat shock protein 70 (Hsp 70) family protein; Its function is described as ATP binding; Located in plasma membrane, chloroplast; Expressed in 24 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Heat shock protein 70, conserved site (InterPro-IPR018181), Heat shock protein Hsp70 (InterPro-IPR001023), Heat shock protein 70 (InterPro-IPR013126); BEST Arabidopsis thaliana protein match is- heat shock protein 70 (Hsp 70) family protein (TAIR-AT1G11660.1); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazo [...] (867 aa)
   
      0.900
PDIL2-2
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response (447 aa)
     
   
  0.864
SDF2
Stromal cell-derived factor 2-like protein precursor; Involved in the endoplasmic reticulum (ER) protein quality control and unfolded protein response. May be involved in the quality control of glycoproteins. Forms a complex in the ER with ERDJ3B and MED37A/BIP1 which is required for the proper accumulation and function of the surface-exposed leucine-rich repeat receptor kinases EFR involved in pathogen-associated molecular pattern (PAMP) triggered immunity (218 aa)
     
   
  0.841
CNX1
Calnexin homolog 1; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity) (530 aa)
     
        0.840
AT4G29520
Uncharacterized protein AT4g29520; Located in endoplasmic reticulum, plasma membrane; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Saposin B (InterPro-IPR008139); Has 137 Blast hits to 137 proteins in 50 species- Archae - 2; Bacteria - 0; Metazoa - 41; Fungi - 10; Plants - 36; Viruses - 0; Other Eukaryotes - 48 (source- NCBI BLink) (306 aa)
     
        0.836
BIP1
Mediator of RNA polymerase II transcription subunit 37a; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and the genera [...] (669 aa)
   
      0.835
UTR1
UDP-galactose/UDP-glucose transporter 1; Essential sugar transporter required for the transport of UDP-galactose and UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum, to ensure quality control of protein folding. Essential for pollen development and involved in embryo sac progress (332 aa)
     
   
0.831
BIP2
Mediator of RNA polymerase II transcription subunit 37f; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general [...] (668 aa)
   
      0.823
BIP3
Probable mediator of RNA polymerase II transcription subunit 37b; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and t [...] (675 aa)
   
      0.782
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (13%) [HD]