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MGH3 protein (Arabidopsis thaliana) - STRING interaction network
"MGH3" - Histone H3 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MGH3Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity) (137 aa)    
Predicted Functional Partners:
HAG4
Histone acetyltransferase MYST1; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates ’Lys-5’ of histone H4 (H4K5ac) (PubMed-17877703, PubMed-19040736, PubMed-22170978, PubMed-23273925). Essential for gametophyte development (PubMed-19040736). Involved in DNA repair after UV-B exposure (PubMed-22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed-23273925) (445 aa)
       
  0.963
HAG5
MYST-like histone acetyltransferase 2; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates ’Lys-5’ of histone H4 (H4K5ac) (PubMed-16648464, PubMed-17877703). Essential for gametophyte development (PubMed-19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed-23273925) (445 aa)
       
  0.963
ASF1B
Histone chaperone ASF1B; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (218 aa)
     
 
  0.950
SGA2
Histone chaperone ASF1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (By similarity). While encoded by a region of the Arabidopsis thaliana genome that is homologous to the Brassica S- locus for self incompatibility, this protein may not play the same role in Arabidopsis thaliana (196 aa)
     
 
  0.950
HAF01
Transcription initiation factor TFIID subunit 1-A; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex (By similarity) (1919 aa)
       
 
  0.944
HMG
High mobility group; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the n [...] (646 aa)
     
 
  0.941
ING1
INHIBITOR OF GROWTH 1; Histone-binding component that specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes (234 aa)
       
  0.915
ING2
INHIBITOR OF GROWTH 2; Histone-binding component that specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes (328 aa)
       
  0.915
AT5G02570
Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (132 aa)
     
 
  0.912
IBM1
Increase in bonsai methylation 1; Histone demethylase that demethylates ’Lys-9’ (H3K9me) of histone H3 with a specific activity for H3K9me2 and H3K9me1. No activity on H3K9me3, H3K4me3/2/1, H3K27me3/2/1 and H3K36me3/2/1. Involved in the control of several developmental processes by protecting genes from silencing. Demethylates H3K9me2 in the promoter regions of RDR2 and DCL3 and mediates the repression of ectopic non-CpG methylation at RDR2, DCL3 and APC13 loci. Protects also a large number of transcribed genes from non-CpG methylation. May regulate gene expression via a pathway involv [...] (1049 aa)
       
  0.912
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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