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CDKB2;2 protein (Arabidopsis thaliana) - STRING interaction network
"CDKB2;2" - Cyclin-dependent kinase, expressed in flowers and suspension cell culture, expression peaks during M phase in synchronized cultures. Required for proper organization of the shoot apical meristem and for hormone signaling. Expressed in the shoot apical meristem. Involved in regulation of the G2/M transition of the mitotic cell cycle in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CDKB2;2Cyclin-dependent kinase, expressed in flowers and suspension cell culture, expression peaks during M phase in synchronized cultures. Required for proper organization of the shoot apical meristem and for hormone signaling. Expressed in the shoot apical meristem. Involved in regulation of the G2/M transition of the mitotic cell cycle; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily (315 aa)    
Predicted Functional Partners:
CKS1
Catalytic subunit of cyclin dependent kinase 1. physically interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle; Belongs to the CKS family (87 aa)
     
  0.999
CYC1BAT
Cyclin family protein; Encodes a cyclin whose expression is reduced in response to high salt (445 aa)
     
 
  0.999
MEE34
26S proteasome non-ATPase regulatory subunit 7 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (310 aa)
     
 
  0.995
EIF2B
Eukaryotic translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2- GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction ca [...] (268 aa)
       
      0.995
CKS2
Cyclin-dependent kinases regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (83 aa)
     
  0.971
AUR1
Serine/threonine-protein kinase Aurora-1; Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division. Transcripts are abundant in tissues rich in dividing cells like roots and flowers but are low or absent in fully expanded leaves and stems. In interphase cells, the protein is predominantly nuclear. During mitosis, the protein associates with plant-specific cytoskeletal structures (preprophase band, phragmoplast, nascent cell plate) that are necessary for cytokinesis as well as with the microtubule spindle. It specifically phosphorylates Ser10 of hist [...] (294 aa)
   
 
0.963
AUR2
Serine/threonine-protein kinase Aurora-2; Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division. Transcripts are abundant in tissues rich in dividing cells like roots and flowers but are low or absent in fully expanded leaves and stems. In interphase cells, the protein is predominantly nuclear. During mitosis, the protein associates with plant-specific cytoskeletal structures (preprophase band, phragmoplast, nascent cell plate) that are necessary for cytokinesis as well as with the microtubule spindle (288 aa)
   
 
0.956
AT4G14330
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Probable plus end-directed motor protein that may contribute to the transport of Golgi-derived vesicles in the phragmoplast (869 aa)
     
 
  0.939
3xHMG-box2
HMG (high mobility group) box protein; Its function is described as sequence-specific DNA binding transcription factor activity; Located in nucleus, chloroplast; Expressed in 20 plant structures; Expressed during 11 growth stages; Contains the following InterPro domains- High mobility group, superfamily (InterPro-IPR009071), High mobility group, HMG1/HMG2 (InterPro-IPR000910); BEST Arabidopsis thaliana protein match is- HMG (high mobility group) box protein (TAIR-AT4G11080.1); Has 73209 Blast hits to 39847 proteins in 2254 species- Archae - 389; Bacteria - 7210; Metazoa - 37524; Fungi [...] (456 aa)
     
      0.936
CYCP2;1
Cyclin-U1-1; Cyclin p2;1 (CYCP2;1); Contains the following InterPro domains- Negative regulatory factor PREG (InterPro-IPR012389), Cyclin-like (InterPro-IPR011028), Cyclin-related 2 (InterPro-IPR013922), Cyclin (InterPro-IPR006670); BEST Arabidopsis thaliana protein match is- cyclin p4;1 (TAIR-AT2G44740.1); Has 1311 Blast hits to 1303 proteins in 220 species- Archae - 0; Bacteria - 18; Metazoa - 222; Fungi - 576; Plants - 231; Viruses - 0; Other Eukaryotes - 264 (source- NCBI BLink) (210 aa)
       
 
  0.935
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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