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IGMT2 protein (Arabidopsis thaliana) - STRING interaction network
"IGMT2" - O-methyltransferase family protein in Arabidopsis thaliana
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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IGMT2O-methyltransferase family protein; Involved in indole glucosinolate biosynthesis. Catalyzes methoxylation reactions of the glucosinolate indole ring. Converts the hydroxy intermediates 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1- methoxy-indol-3-yl-methylglucosinolate (1MO-I3M), respectively (373 aa)    
Predicted Functional Partners:
CYP81F2
Cytochrome P450, family 81, subfamily F, polypeptide 2; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (PubMed-21317374). Contri [...] (491 aa)
     
   
  0.851
IGMT3
O-methyltransferase family protein; Involved in indole glucosinolate biosynthesis. Catalyzes methoxylation reactions of the glucosinolate indole ring. Converts the hydroxy intermediates 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1- methoxy-indol-3-yl-methylglucosinolate(1MO-I3M), respectively (373 aa)
   
   
0.844
GGP1
Gamma-glutamyl peptidase 1; Involved in glucosinolate biosynthesis. Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates. The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis (PubMed-19483696, PubMed-21712415). Converts phenylacetohydroximoyl-GSH to benzylglucosinolate (PubMed-19483696). Can use the GSH conjugate of the camalexin intermediate IAN (GS-IAN) as substrate. Required for the biosynthesis of camalexin, a pathogen-inducible phytoalexin with antib [...] (250 aa)
     
   
  0.739
AT3G02840
ARM repeat superfamily protein (379 aa)
     
   
  0.681
MYB51
Myb domain protein 51; Transcription factor positively regulating indolic glucosinolate biosynthetic pathway genes (352 aa)
     
   
  0.674
CYP91A2
Cytochrome P450 81F1; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (500 aa)
           
  0.670
CYP81F3
Member of CYP81F; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (501 aa)
           
  0.670
AT1G26380
FAD-binding Berberine family protein; Flavin-dependent oxidoreductase involved in the biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitrile (4-OH- ICN), a cyanogenic metabolite required for inducible pathogen defense. Converts indole cyanohydrin into indole-3-carbonyl nitrile (ICN) (535 aa)
     
        0.601
B120
S-locus lectin protein kinase-like protein (849 aa)
     
   
  0.561
CYP81F4
Member of CYP81F; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediate. This hydroxy intermediates is converted to 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (501 aa)
           
  0.558
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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