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IGMT4 protein (Arabidopsis thaliana) - STRING interaction network
"IGMT4" - O-methyltransferase-like protein in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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IGMT4O-methyltransferase-like protein; Involved in indole glucosinolate biosynthesis. Catalyzes methoxylation reactions of the glucosinolate indole ring. Converts the hydroxy intermediates 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1- methoxy-indol-3-yl-methylglucosinolate(1MO-I3M), respectively (373 aa)    
Predicted Functional Partners:
CYP91A2
Cytochrome P450 81F1; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (500 aa)
           
  0.670
CYP81F3
Member of CYP81F; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (501 aa)
           
  0.670
GGP1
Gamma-glutamyl peptidase 1; Involved in glucosinolate biosynthesis. Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates. The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis (PubMed-19483696, PubMed-21712415). Converts phenylacetohydroximoyl-GSH to benzylglucosinolate (PubMed-19483696). Can use the GSH conjugate of the camalexin intermediate IAN (GS-IAN) as substrate. Required for the biosynthesis of camalexin, a pathogen-inducible phytoalexin with antib [...] (250 aa)
     
   
  0.656
AT1G55450
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (320 aa)
     
        0.604
CYP81F2
Cytochrome P450, family 81, subfamily F, polypeptide 2; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 4-hydroxy-indol-3-yl- methylglucosinolate (4OH-I3M) and/or 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediates. These hydroxy intermediates are converted to 4-methoxy-indol-3-yl- methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (PubMed-21317374). Contri [...] (491 aa)
     
   
  0.587
DREB2A
DRE-binding protein 2A; Transcriptional activator that binds specifically to the DNA sequence 5’-[AG]CCGAC-3’. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (335 aa)
     
      0.573
CYP81F4
Member of CYP81F; Involved in indole glucosinolate biosynthesis. Catalyzes hydroxylation reactions of the glucosinolate indole ring. Converts indol-3-yl-methylglucosinolate (I3M) to 1-hydroxy-indol-3-yl- methylglucosinolate (1OH-I3M) intermediate. This hydroxy intermediates is converted to 1-methoxy-indol-3-yl- methylglucosinolate (1MO-I3M) by indole glucosinolate methyltransferase 1 and 2 (IGMT1 and IGMT2) (501 aa)
           
  0.557
MYB51
Myb domain protein 51; Transcription factor positively regulating indolic glucosinolate biosynthetic pathway genes (352 aa)
     
   
  0.524
ABCG36
PENETRATION 3; Key factor that controls the extent of cell death in the defense response. Neccessary for both callose deposition and glucosinolate activation in response to pathogens. Required for limiting invasion by nonadapted powdery mildews. Confers resistance to cadmium (Cd) and lead (Pb), probably as an efflux pump of Cd2+ or Cd conjugates, and possibly, of chemicals that mediate pathogen resistance (1469 aa)
     
        0.501
AT1G33600
Leucine-rich repeat-containing protein (478 aa)
     
      0.472
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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