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WAK1 protein (Arabidopsis thaliana) - STRING interaction network
"WAK1" - Wall-associated receptor kinase 1 in Arabidopsis thaliana
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
WAK1Wall-associated receptor kinase 1; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. Required during plant’s response to pathogen infection and in plant defense against heavy metal toxicity. Phosphorylates the oxygen-evolving enhancer protein 2 (OEE2) in an GRP-3-dependent manner (735 aa)    
Predicted Functional Partners:
Encodes a glycine-rich protein that is expressed mainly in stems and leaves. mRNA levels are upregulated in response to ABA, salicylic acid and ethylene but downregulated in response to dessication (145 aa)
Protein of unknown function (DUF567); Encodes LURP1, a member of the LURP cluster (late upregulated in response to Hyaloperonospora parasitica) which exhibits a pronounced upregulation after recognition of the pathogenic oomycte H. parasitica. LURP1 is required for full basal defense to H. parasitica and resistance to this pathogen mediated by the R-proteins RPP4 and RPP5 (207 aa)
Serine/Threonine kinase kinase ATP-binding sugar-binding kinase carbohydrate-binding protein; Unknown protein; Has 4 Blast hits to 4 proteins in 1 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 4; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (52 aa)
Oxygen-evolving enhancer protein 2-1, chloroplastic; Encodes a 23 kD extrinsic protein that is part of photosystem II and participates in the regulation of oxygen evolution; Belongs to the psbP family (263 aa)
Kinase associated protein phosphatase; Dephosphorylates the Ser/Thr receptor-like kinase RLK5. May function as a signaling component in a pathway involving RLK5. Binds and dephosphorylates CLAVATA1 (CLV1). Functions as a negative regulator of the CLV1 signaling in plant development. Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop. Dephosphorylation of SERK1 controls SERK1 internalization. Component of a signaling pathway which mediates adaptation to NaCl stress. Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway (591 aa)
Protein kinase family protein with leucine-rich repeat domain; Its function is described as protein serine/threonine kinase activity, protein tyrosine kinase activity, protein kinase activity, ATP binding; Involved in transmembrane receptor protein tyrosine kinase signaling pathway, protein amino acid phosphorylation; Located in endomembrane system; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Protein kinase, ATP binding site (InterPro-IPR017441), Serine/threonine-protein kinase domain (InterPro-IPR002290), Leucine-rich r [...] (1120 aa)
Eukaryotic aspartyl protease family protein; Aspartyl protease involved in a homeostatic feedback mechanism regulating systemic immunity. Has only mild or no influence on local defenses. Acts downstream of salicylic acid to suppress systemic immunity (464 aa)
Uncharacterized protein AT4g03450; Ankyrin repeat family protein; Contains the following InterPro domains- Ankyrin repeat-containing domain (InterPro-IPR020683), Ankyrin repeat (InterPro-IPR002110); BEST Arabidopsis thaliana protein match is- Ankyrin repeat family protein (TAIR-AT4G03440.1); Has 22492 Blast hits to 11630 proteins in 488 species- Archae - 24; Bacteria - 1675; Metazoa - 12211; Fungi - 1719; Plants - 2554; Viruses - 43; Other Eukaryotes - 4266 (source- NCBI BLink) (641 aa)
Calcium-binding EF-hand family protein; Potential calcium sensor (191 aa)
Ankyrin repeat-containing protein BDA1; Involved in plant defense. Required for basal resistance against Pseudomonas syringae pv. tomato DC3000. Required for resistance against nonpathogenic bacteria. May be involved in signaling components that function downstream of SNC2 and upstream of NPR1 and WRKY70 to regulate defense responses (426 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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