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ZYP1b protein (Arabidopsis thaliana) - STRING interaction network
"ZYP1b" - Myosin heavy chain-related protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ZYP1bMyosin heavy chain-related protein; One of two nearly identical proteins (ZYP1a) identified by similarity to transverse filament (TF) proteins. These proteins are involved in chromosome synapsis during meiosis I and localize to the synaptonemal complex (SC). Single mutants have reduced fertility and double mutants (induced by RNAi) have severely reduced fertility (856 aa)    
Predicted Functional Partners:
ASY1
DNA-binding HORMA family protein; Required for normal meiosis in male and female gametophytes. Plays a crucial role in coordinating the activity of DMC1, a key member of the homologous recombination machinery. Acts at the interface between the developing chromosome axes and the recombination machinery to ensure DMC1- mediated interhomolog recombination (596 aa)
           
  0.983
DMC1
Meiotic recombination protein DMC1 homolog; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Mediates interhomolog recombination during meiosis (344 aa)
           
  0.952
RCK
ATP binding;ATP-dependent helicases;DNA helicases; DNA helicase required for crossover formation, complete synapsis of homologous chromosomes and bivalent formation during meiosis. Is specific to recombination events resulting in interference-sensitive crossovers (class I meiotic crossover) (1133 aa)
           
  0.937
ASY3
Meiosis-specific protein ASY3; Required for normal meiosis in male and female gametophytes. Acts with ASY1 at the interface between the developing chromosome axes and the recombination machinery to ensure interhomolog recombination. Required for synaptonemal complex formation during meiosis (793 aa)
           
  0.929
ZIP1
Zinc transporter 1 precursor; A member of Zrt- and Irt-related protein (ZIP) family. transcript is induced in response to zinc deficiency in the root (355 aa)
           
  0.903
RAD51
RAS associated with diabetes protein 51; Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA (By similarity). Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) generated by AtSPO11-1 and in homologous recombination. Its function is dispensable for vegetative growth and root mitosis (342 aa)
           
  0.897
DFO
Uncharacterized protein At1g07060; Unknown protein; Has 30 Blast hits to 30 proteins in 10 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 30; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (233 aa)
           
  0.891
AT4G24710
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Plays a key role in chromosome recombination during meiosis. Mediates meiotic chromosome remodeling and crossover maturation (475 aa)
           
  0.863
HEI10
E3 ubiquitin-protein ligase CCNB1IP1 homolog; Ubiquitin E3 ligase required for class I crossing-over (CO) formation during meiosis (304 aa)
           
  0.861
MLH1
DNA mismatch repair protein MLH1; Involved in DNA mismatch repair (MMR), correcting insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in promoting meiotic crossing-over and is [...] (737 aa)
           
  0.861
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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