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SPDS1 protein (Arabidopsis thaliana) - STRING interaction network
"SPDS1" - Spermidine synthase in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SPDS1Spermidine synthase (378 aa)    
Predicted Functional Partners:
NLP1
Encodes N-carbamoylputrescine amidohydrolase that is involved in putrescine and polyamine biosynthesis; Belongs to the carbon-nitrogen hydrolase superfamily (326 aa)
       
  0.996
SAMDC
S-adenosylmethionine decarboxylase proenzyme 1; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family (366 aa)
   
 
  0.995
EMB1873
Porphyromonas-type peptidyl-arginine deiminase family protein; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine (383 aa)
         
  0.976
ADC2
Encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. ADC2 is stress-inducible (osmotic stress). Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Overexpression causes phenotypes similar to GA-deficient plants and these plants show reduced levels of GA due to lower expression levels of AtGA20ox1, AtGA3ox3 and AtGA3ox1; Belongs to the Orn/Lys [...] (711 aa)
         
  0.972
ADC1
Encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Promoter region of ADC1 contains 742-bp AT-rich transposable element, called AtATE, that belongs to the MITE families of repetitive elements (702 aa)
         
  0.972
PAO1
Polyamine oxidase 1; Flavoenzyme that catalyzes the oxidation of the secondary amino group of spermine, norspermine and N(1)- acetylspermine. Substrate preference is norspermine > spermine > N(1)-acetylspermine. No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates. Plays an important role in the regulation of polyamine intracellular concentration; Belongs to the flavin monoamine oxidase family (472 aa)
       
  0.967
PAO4
Encodes a peroxisomal polyamine oxidase, involved in the back-conversion polyamine degradation pathway. Among the five polyamine oxidases in the Arabidopsis genome, PAO4 is the major isoform in root peroxisomes; Belongs to the flavin monoamine oxidase family (497 aa)
       
  0.961
AT3G25570
Adenosylmethionine decarboxylase family protein; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development (349 aa)
   
 
  0.960
AT5G15950
Adenosylmethionine decarboxylase family protein; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family (362 aa)
   
 
  0.954
AT5G53850
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1; Haloacid dehalogenase-like hydrolase family protein; Its function is described as in 7 functions; Involved in L-methionine salvage from methylthioadenosine, L-methionine salvage, metabolic process; Located in chloroplast; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Haloacid dehalogenase-like hydrolase (InterPro-IPR005834), 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (InterPro-IPR010041), Class II aldolase/adducin, N-terminal [...] (507 aa)
 
 
  0.953
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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