• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
MAP70-2 protein (Arabidopsis thaliana) - STRING interaction network
"MAP70-2" - Microtubule-associated proteins 70-2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP70-2Microtubule-associated proteins 70-2; Plant-specific protein that interact with microtubules (634 aa)    
Predicted Functional Partners:
AT4G32190
Myosin heavy chain-related protein; Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (783 aa)
       
      0.762
MAP70-5
Microtubule-associated proteins 70-5; Plant-specific protein that interact with microtubules and regulates microtubule dynamics. May play a role in anisotropic cell expansion and organ growth. In association with MAP70.1, is essential for the normal banding pattern of secondary cell wall and for the proper development of xylem tracheary elements and wood formation (513 aa)
       
   
0.762
HUB1
E3 ubiquitin-protein ligase BRE1-like 1; E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6. Required for the regulation of flowering time and defense against necrotrophic fungal pathogens. Involved in the control of seed dormancy and germination; Belongs to the BRE1 family (878 aa)
       
      0.762
AT1G20770
Unknown protein; Has 59 Blast hits to 59 proteins in 24 species- Archae - 0; Bacteria - 0; Metazoa - 26; Fungi - 4; Plants - 29; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (215 aa)
       
      0.762
AT5G46070
Guanylate-binding family protein; Its function is described as GTP binding, GTPase activity; Involved in immune response; Located in nucleolus, chloroplast; Expressed in 24 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Guanylate-binding protein, N-terminal (InterPro-IPR015894), Guanylate-binding protein, C-terminal (InterPro-IPR003191); BEST Arabidopsis thaliana protein match is- guanylate-binding family protein (TAIR-AT1G03830.2); Has 135716 Blast hits to 74856 proteins in 3470 species- Archae - 1642; Bacteria - 27962; Metazoa - 58309; F [...] (1082 aa)
     
   
  0.605
AT5G42220
Ubiquitin-like superfamily protein; Contains the following InterPro domains- Ubiquitin subgroup (InterPro-IPR019956), Ubiquitin conserved site (InterPro-IPR019954), Ubiquitin (InterPro-IPR000626), Ubiquitin supergroup (InterPro-IPR019955); BEST Arabidopsis thaliana protein match is- Ubiquitin-like superfamily protein (TAIR-AT5G25270.1); Has 12270 Blast hits to 6672 proteins in 779 species- Archae - 2; Bacteria - 272; Metazoa - 5255; Fungi - 1469; Plants - 2655; Viruses - 175; Other Eukaryotes - 2442 (source- NCBI BLink) (879 aa)
           
  0.581
NOXY38
Tetratricopeptide repeat (TPR)-containing protein; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria; Belongs to the CLU family (1419 aa)
           
  0.581
MCM2
Minichromosome maintenance (MCM2/3/5) family protein; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. May play a crucial role in the control of de-differentiation and cell proliferation processes required for lateral root formation. Is essential for embryo development. Is involved in the geminivirus mungbean yellow mosaic virus (MYMV) DNA replication, presumably in conjunction with other host factors (936 aa)
           
  0.581
SMC3
Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis; Belongs to the SMC family. SMC4 subfamily (1244 aa)
     
   
  0.549
ATSPO11-1
Spo11/DNA topoisomerase VI, subunit A protein; Encodes AtSPO11-1, one of the three Arabidopsis homologues of the archaeal DNA topoisomerase VIA subunit (topo VIA). Required for meiotic recombination. AtSPO11-1 and AtSPO11-2 have overlapping functions (i.e. both required for meiotic recombination) whereas AtSPO11-3 functions in DNA replication. AtSPO11-1 accumulates in foci in early G2. At 1 h post-S phase, no foci are observed, but by 3 h a majority (80%) of meiocytes at this time point contain >50 foci. However, by 5 h, AtSPO11-1 foci are no longer detectable. This suggests that [...] (362 aa)
     
   
  0.536
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (8%) [HD]