STRINGSTRING
MYC2 protein (Arabidopsis thaliana) - STRING interaction network
"MYC2" - Transcription factor MYC2 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYC2Transcription factor MYC2; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA- dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5’-CACATG-3’), and to the G-box (5’-CACNTG-3’) and Z-box (5’-ATACGTGT-3’) of promoters. Binds directly to the pro [...] (623 aa)    
Predicted Functional Partners:
JAZ1
Protein TIFY 10A; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high- affinity jasmonates coreceptor (253 aa)
      
  0.999
JAZ3
Protein TIFY 6B; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY6B/JAZ3 interaction. Acts as a negative regulator of MYC2 function. Feed-back regulated by MYC2 (352 aa)
      
  0.999
JAZ10
Protein TIFY 9; Modulator of growth inhibition. Isoform 2 and isoform 3, but not isoform 1, confer a strong methyl-jasmonate insensitivity. Not involved in the growth response to salicylic acid or indole-3- acetic acid. Isoform 3 acts as an endogenous repressor of JA signal output in JA-stimulated cells (PubMed-19151223) (197 aa)
      
  0.999
TIFY10B
Protein TIFY 10B; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10B/JAZ2 interaction. Activated by MYC2, MYC3 and MYC4 transcription factors (249 aa)
      
  0.999
JAZ5
Protein TIFY 11A; Repressor of jasmonate responses (274 aa)
      
  0.999
TIFY7
Protein TIFY 7; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY7/JAZ9 interaction (267 aa)
      
  0.999
JAZ6
Protein TIFY 11B; Repressor of jasmonate responses (269 aa)
      
  0.999
JAZ12
Protein TIFY 3B; Repressor of jasmonate responses (187 aa)
      
  0.999
JAZ11
Protein TIFY 3A; Repressor of jasmonate (JA) responses. Targets MYC2, MYC3 and MYC4 that are JA-depedent transcription activators (238 aa)
        
  0.999
JAZ4
Protein TIFY 6A; Repressor of jasmonate responses (310 aa)
        
  0.999
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >