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SBT3.5 protein (Arabidopsis thaliana) - STRING interaction network
"SBT3.5" - Subtilisin-like protease SBT3.5 in Arabidopsis thaliana
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
SBT3.5Subtilisin-like protease SBT3.5; Serine protease that cleaves the pectin methylesterase 17 (PME17) protein to release the PME17 mature form in the apoplasm (774 aa)    
Predicted Functional Partners:
Plant invertase/pectin methylesterase inhibitor superfamily; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family (511 aa)
Cytochrome P450 monooxygenase (503 aa)
Thioredoxin superfamily protein; Its function is described as protein disulfide oxidoreductase activity; Involved in defense response to fungus, incompatible interaction; Located in cellular_component unknown; Expressed in 16 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains- DSBA oxidoreductase (InterPro-IPR001853), Thioredoxin-like fold (InterPro-IPR012336); Has 2126 Blast hits to 2126 proteins in 739 species- Archae - 17; Bacteria - 1478; Metazoa - 14; Fungi - 129; Plants - 62; Viruses - 0; Other Eukaryotes - 426 (source- NCBI BLink) (217 aa)
Plant invertase/pectin methylesterase inhibitor superfamily protein; Pectin methylesterase (PME) inhibitor that can target the root-expressed PME17, regulate de-methylesterification of pectins in roots and affects root growth; Belongs to the PMEI family (199 aa)
Rapid alkalinization factor 23; Encodes RALF23, a member of a diversely expressed predicted peptide family showing sequence similarity to tobacco Rapid Alkalinization Factor (RALF), and is believed to play an essential role in the physiology of Arabidopsis. Consists of a single exon and is characterized by a conserved C-terminal motif and N-terminal signal peptide. RALF23 is significantly downregulated by brassinolide treatment of seedlings. Overexpression of AtRALF23 impairs brassinolide-induced hypocotyls elongation, and mature overexpressing plants are shorter and bushier. RALF2 [...] (138 aa)
Galactinol synthase 4; Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance (By similarity) (334 aa)
IQ domain-containing protein IQM1; Involved in the modulation of stomatal movement. Promotes stomatal opening. May play a role in the regulation of chitin signaling. May be involved in biotic and abiotic stress responses (526 aa)
CBL-interacting serine/threonine-protein kinase 13; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium- dependent manner (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily (502 aa)
Pyridoxal 5’-phosphate synthase subunit PDX1.1; Catalyzes the formation of pyridoxal 5’-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen- generating photosensitizers (309 aa)
Subtilisin-like protease SBT6.1; Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane-associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-t [...] (1038 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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