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MOS2 protein (Arabidopsis thaliana) - STRING interaction network
"MOS2" - D111/G-patch domain-containing protein in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MOS2D111/G-patch domain-containing protein; Has single homolog in Arabidopsis, also homologs in human, mouse and C. elegans; contains one G-patch domain (known to mediate RNA-protein interactions) and two KOW domains (may bind RNA and/or protein); localized to the nucleus; mutant suppresses high SA levels and constitutive disease resistance in snc1 npr1 background; required for basal resistance against Pseudomonas syringae maculicola ES4326 and R gene-mediated resistance specified by RPM1, PPS4 and RPP4; (462 aa)    
Predicted Functional Partners:
EMB3011
Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7; Involved in pre-mRNA splicing by mediating structural transitions of the spliceosome during the catalytic step. Facilitates expression of genes involved in auxin-mediated development including male-gametophyte transmission, apical-basal patterning of embryonic and gynoecium development, stamen development, phyllotactic flower positioning, and vascular development. Also involved in root-meristem maintenance and planar polarity of root-hair positioning. Acts as a component of RNA silencing that regulates distinct classes of endog [...] (1255 aa)
     
  0.979
MEE29
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH6; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP2 sub-subfamily (1044 aa)
     
  0.978
CDC5
Cell division cycle 5-like protein; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage; Belongs to the CEF1 family (844 aa)
     
 
  0.976
AT4G16680
P-loop containing nucleoside triphosphate hydrolases superfamily protein; May be involved in pre-mRNA splicing (656 aa)
     
  0.975
ESP3
Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1; Encodes a homolog of the yeast PRP2 protein, one of four related DEAH RNA helicases identified as essential cofactors for RNA splicing (1044 aa)
     
  0.975
AT2G29210
Splicing factor PWI domain-containing protein; Involved in RNA splicing; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Splicing factor PWI (InterPro-IPR002483); BEST Arabidopsis thaliana protein match is- Polynucleotidyl transferase, ribonuclease H-like superfamily protein (TAIR-AT3G12440.1); Has 159601 Blast hits to 84623 proteins in 2432 species- Archae - 148; Bacteria - 15367; Metazoa - 68765; Fungi - 25678; Plants - 14277; Viruses - 2838; Other Eukaryotes - 32528 (source- NCBI BLink) (878 aa)
     
    0.972
MOS4
Pre-mRNA-splicing factor SPF27 homolog; Encodes MOS4 (Modifier of snc1, 4), a nuclear protein homologous to human Breast Cancer-Amplified Sequence (BCAS2). MOS4 interacts with AtCDC5 and PRL1. All three proteins are essential for plant innate immunity (253 aa)
     
 
  0.971
ABH1
Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state [...] (848 aa)
     
 
  0.970
PRL1
Protein pleiotropic regulatory locus 1; Pleiotropic regulator of glucose, stress and hormone responses. Also regulates cytochrome P450 CYP90A1/CPD. Coordinates the expression of hormone- and stress-related genes and genes related to cell wall modification and growth, leading to altered sugar-dependent growth and developmental responses. Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. By suppressing the expression of several (1)O(2)- responsive genes, PRL1 seems to play a major rol [...] (486 aa)
     
 
  0.966
CBP20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with t [...] (257 aa)
     
 
  0.962
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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