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RTNLB24 protein (Arabidopsis thaliana) - STRING interaction network
"RTNLB24" - 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RTNLB243beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1; Encodes an enzyme with 3&#946;-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound (439 aa)    
Predicted Functional Partners:
AT5G58000
Reticulon-like protein B21; Reticulon family protein; Located in endoplasmic reticulum, chloroplast; Contains the following InterPro domains- Reticulon (InterPro-IPR003388); BEST Arabidopsis thaliana protein match is- Reticulon family protein (TAIR-AT2G20590.1); Has 1128 Blast hits to 1113 proteins in 146 species- Archae - 0; Bacteria - 2; Metazoa - 759; Fungi - 49; Plants - 88; Viruses - 4; Other Eukaryotes - 226 (source- NCBI BLink) (487 aa)
           
  0.951
AT4G28430
Reticulon-like protein B18; Reticulon family protein; Involved in biological_process unknown; Located in endoplasmic reticulum, chloroplast; Expressed in 11 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Reticulon (InterPro-IPR003388); BEST Arabidopsis thaliana protein match is- Reticulon family protein (TAIR-AT2G20590.1); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (457 aa)
           
  0.909
AT1G68230
Reticulon-like protein B14; Reticulon family protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endoplasmic reticulum; Expressed in 21 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains- Reticulon (InterPro-IPR003388); BEST Arabidopsis thaliana protein match is- Reticulon family protein (TAIR-AT2G46170.1); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- [...] (162 aa)
           
  0.903
BTI1
VIRB2-interacting protein 1; Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus (275 aa)
           
  0.901
CYP51G1
Sterol 14-demethylase; Involved in sterol biosynthesis. Catalyzes the 14-alpha demethylation of obtusifoliol to 4 alpha-methyl-5 alpha-ergosta- 8,14,24(28)-trien-3 beta-ol (488 aa)
     
 
  0.890
ERG28
Homolog of yeast ergosterol28 (ERG28); Involved in biological_process unknown; Located in endomembrane system, integral to membrane; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Erg28-like (InterPro-IPR005352); Has 223 Blast hits to 223 proteins in 105 species- Archae - 0; Bacteria - 0; Metazoa - 67; Fungi - 94; Plants - 48; Viruses - 0; Other Eukaryotes - 14 (source- NCBI BLink) (129 aa)
     
 
  0.876
AT3G10260
Reticulon-like protein B8; Reticulon family protein; Contains the following InterPro domains- Reticulon (InterPro-IPR003388); BEST Arabidopsis thaliana protein match is- Reticulon family protein (TAIR-AT3G61560.1); Has 1060 Blast hits to 1060 proteins in 78 species- Archae - 0; Bacteria - 0; Metazoa - 591; Fungi - 0; Plants - 458; Viruses - 0; Other Eukaryotes - 11 (source- NCBI BLink) (267 aa)
           
  0.862
PAF2
Proteasome subunit alpha type-1-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May play a role in thiol biosynthesis and arsenic tolerance in association with PAF1/ARS5 (277 aa)
     
 
  0.836
RTNLB3
Reticulan like protein B3 (RTNLB3); Contains the following InterPro domains- Reticulon (InterPro-IPR003388); BEST Arabidopsis thaliana protein match is- VIRB2-interacting protein 3 (TAIR-AT5G41600.1) (271 aa)
           
  0.836
BTI3
VIRB2-interacting protein 3; Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus (257 aa)
           
  0.831
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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