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AT1G47578 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G47578" - Biotin/lipoate A/B protein ligase family in Arabidopsis thaliana
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Known Interactions
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Predicted Interactions
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textmining
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protein homology
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AT1G47578Biotin/lipoate A/B protein ligase family; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) (280 aa)    
Predicted Functional Partners:
AT5G08415
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (394 aa)
 
  0.996
At2g20860
Lipoic acid synthase 1; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (374 aa)
 
  0.993
MOD1
MOSAIC DEATH 1; Catalyzes the NAD-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Catalyzes the last reduction step in the de novo synthesis cycle of fatty acids. Involved in the elongation cycle of fatty acids which are used in lipid metabolism. Required for normal plant growth (390 aa)
   
 
  0.888
KASI
3-ketoacyl-acyl carrier protein synthase I; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity) (489 aa)
     
  0.884
FTRA2
Ferredoxin/thioredoxin reductase subunit A (variable subunit) 2 (184 aa)
   
 
  0.841
FAB1
Fatty acid biosynthesis 1; Essential protein that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-16 and C-16 to unsaturated C-18 fatty acids. Confers resistance to low temperatures by maintaining chloroplast membranes integrity. Involved in the regulation of fatty acids ratios during seed metabolism. Required for embryo development, especially at the transition from the globular to the heart stage (541 aa)
     
  0.837
LIP2
Lipoyltransferase 2; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (Probable) (235 aa)
   
   
 
0.816
AT2G04540
Beta-ketoacyl synthase; Catalyzes all the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Able to elongate saturated acyl chains from 4 to at least 16 carbons. Uses malonyl-CoA but not acetyl-CoA as primer substrate. When expressed in a heterologous system, reveals a bimodal distribution of products, with peaks at C8 and C14-C16. The major product of the reaction (octanoyl-ACP) is required for the lipoylation of essential mitochondrial proteins (461 aa)
       
  0.803
AT4G31050
Plastidial lipoyltransferase 2; Catalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier-protein as a source of lipoyl groups, although octanoyl groups from octanoyl-ACP can also be transferred to the lipoyl domain of apoproteins (278 aa)
   
   
 
0.801
FATB
Fatty acyl-ACP thioesterases B; Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for palmitoyl-ACP versus other acyl-ACPs. Substrate preference is 16-0 > 18-1 > 18-0 > 16-1. Plays an essential role in the supply of saturated fatty acids necessary for plant growth and seed development. Contributes to 16-0 production particularly in flowers. May be involved in the synthesis of long chain fatty acid (412 aa)
         
    0.800
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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