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NUC-L1 protein (Arabidopsis thaliana) - STRING interaction network
"NUC-L1" - Nucleolin in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
Coexpression
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Databases
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[Homology]
Score
NUC-L1Nucleolin; Involved in pre-rRNA processing and ribosome assembly. Is associated with intranucleolar chromatin and pre-ribosomal particles and plays a role in controlling activation and repression of a specific subset of rRNA genes located in distinctive nucleolar organizer regions. Binds specifically rDNA chromatin and may be required to maintain rDNA chromatin structure, but is probably not required for the overall histone methylation status of 45S rRNA genes (557 aa)    
Predicted Functional Partners:
FIB2
Fibrillarin 2; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and the general transcription factors (320 aa)
     
 
  0.959
AT3G18600
DEAD-box ATP-dependent RNA helicase 51 (568 aa)
   
 
  0.958
AT5G04600
RNA recognition motif-containing protein (222 aa)
     
 
  0.953
AT3G26560
ATP-dependent RNA helicase, putative; May be involved in pre-mRNA splicing (1168 aa)
     
 
  0.953
PUR4
Purine biosynthesis 4; Essential to the male gametophyte development. Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1407 aa)
     
      0.949
FIB1
Fibrillarin 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and the general transcription factors (By similarity) (308 aa)
     
 
  0.933
NAP57
Homologue of NAP57; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (’psi’) residues may serve to stabilize the conformation of rRNAs (By similarity) (565 aa)
     
 
  0.928
AT3G05060
Putative nucleolar protein 5-2; Required for 60S ribosomal subunit biogenesis (533 aa)
     
 
  0.926
NOP56
NOP56-like protein (522 aa)
     
 
  0.920
AT5G02870
60S ribosomal protein L4-2 (407 aa)
     
 
  0.915
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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