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NUC-L1 protein (Arabidopsis thaliana) - STRING interaction network
"NUC-L1" - Encodes ATNUC-L1 (NUCLEOLIN LIKE 1), the predominant form of the two nucleolin proteins found in Arabidopsis. This protein is involved in rRNA processing, ribosome biosynthesis, and vascular pattern formation. PARL1 localizes to the nucleolus and parl1 mutants accumulate elevated levels of the unspliced 35S pre-rRNA. parl1 mutants also have defects in cotyledon, leaf, sepal, and petal vein patterning and have reduced stature, reduced fertility, increased bushiness, and reduced root length. The sugar-induced expression of ribosome proteins is also reduced in parl1 mutants in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NUC-L1Encodes ATNUC-L1 (NUCLEOLIN LIKE 1), the predominant form of the two nucleolin proteins found in Arabidopsis. This protein is involved in rRNA processing, ribosome biosynthesis, and vascular pattern formation. PARL1 localizes to the nucleolus and parl1 mutants accumulate elevated levels of the unspliced 35S pre-rRNA. parl1 mutants also have defects in cotyledon, leaf, sepal, and petal vein patterning and have reduced stature, reduced fertility, increased bushiness, and reduced root length. The sugar-induced expression of ribosome proteins is also reduced in parl1 mutants (557 aa)    
Predicted Functional Partners:
FIB2
Mediator of RNA polymerase II transcription subunit 36a; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and the genera [...] (320 aa)
     
  0.997
FIB1
Probable mediator of RNA polymerase II transcription subunit 36b; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre- initiation complex with RNA polymerase II and t [...] (308 aa)
     
  0.995
NOP56
NOP56-like pre RNA processing ribonucleoprotein; NOP56-like protein (522 aa)
     
  0.995
AT3G05060
NOP56-like pre RNA processing ribonucleoprotein; SAR DNA-binding protein, putative, strong similarity to SAR DNA-binding protein-1 (Pisum sativum) GI-3132696; contains Pfam profile PF01798- Putative snoRNA binding domain; encodes NOP58-like protein (533 aa)
     
  0.995
AT5G60990
DEA(D/H)-box RNA helicase family protein; Its function is described as helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; Located in cellular_component unknown; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- RNA helicase, DEAD-box type, Q motif (InterPro-IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro-IPR011545), RNA helicase, ATP-dependent, DEAD-box, conserved site (InterPro-IPR000629), DEAD-like helicase, N-terminal (InterPro-IPR014001), DNA/RNA helicase, C-termin [...] (456 aa)
     
  0.986
AT3G10530
Transducin/WD40 repeat-like superfamily protein; Its function is described as nucleotide binding; Involved in biological_process unknown; Located in CUL4 RING ubiquitin ligase complex; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- WD40 repeat 2 (InterPro-IPR019782), BING4, C-terminal (InterPro-IPR012952), WD40 repeat-like-containing domain (InterPro-IPR011046), WD40-repeat-containing domain (InterPro-IPR017986), WD40/YVTN repeat-like-containing domain (InterPro-IPR015943), WD40 repeat (InterPro-IPR001680), WD40 repeat, sub [...] (536 aa)
     
 
    0.983
AT3G11964
rRNA biogenesis protein RRP5; Involved in the biogenesis of ribosomal RNA (rRNA). Required for the formation of 5.8S rRNA. Required for normal development of female gametophytes (1896 aa)
     
    0.983
AT4G28450
WD repeat and SOF domain-containing protein 1; This gene is predicted to encode a protein with a DWD motif. It can bind to DDB1a in Y2H assays and may be involved in the formation of a CUL4-based E3 ubiquitin ligase (452 aa)
     
 
  0.982
AT1G69070
Nucleolar-like protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Nop14-like protein (InterPro-IPR007276); Has 69842 Blast hits to 35213 proteins in 1572 species- Archae - 363; Bacteria - 20593; Metazoa - 20851; Fungi - 8010; Plants - 2912; Viruses - 517; Other Eukaryotes - 16596 (source- NCBI BLink) (901 aa)
     
 
    0.982
AT4G28200
U3 small nucleolar RNA-associated-like protein; Its function is described as molecular_function unknown; Involved in RNA processing; Located in intracellular; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- RNA-processing protein, HAT helix (InterPro-IPR003107), U3 small nucleolar RNA-associated protein 6 (InterPro-IPR013949); Has 492 Blast hits to 480 proteins in 206 species- Archae - 0; Bacteria - 2; Metazoa - 128; Fungi - 191; Plants - 60; Viruses - 0; Other Eukaryotes - 111 (source- NCBI BLink) (648 aa)
     
 
    0.981
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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