STRINGSTRING
PUB26 protein (Arabidopsis thaliana) - STRING interaction network
"PUB26" - Plant U-box 26 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PUB26Plant U-box 26; Functions as an E3 ubiquitin ligase (421 aa)    
Predicted Functional Partners:
RIN2
RPM1 interacting protein 2; E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN3. Probably not required for RPM1 degradation during HR (578 aa)
           
  0.670
TRB1
Telomere repeat binding factor 1; Binds preferentially double-stranded telomeric repeats (300 aa)
           
  0.670
RIN3
RPM1 interacting protein 3; E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN2. Probably not required for RPM1 degradation during HR (595 aa)
           
  0.631
UBA1
Ubiquitin-activating enzyme 1; Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP (1080 aa)
           
  0.448
RPN12a
Regulatory particle non-ATPase 12A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. May help to control the degradation of one or more factors that repress cytokinin signaling. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development (267 aa)
           
  0.447
UBC10
Ubiquitin-conjugating enzyme 10; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins (148 aa)
           
  0.445
UBC8
Ubiquitin conjugating enzyme 8; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins (149 aa)
           
  0.420
ATS9
non-ATPase subunit 9; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6A is required for proteasome assembly (By similarity) (419 aa)
           
  0.420
AT5G15400
U-box domain-containing protein; Ubiquitin-protein ligase that may function as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chain assembly on substrates monoubiquitinated by another E3 ubiquitin ligase (1038 aa)
           
  0.408
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]