STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT3G49725GTP-binding protein, HflX; Its function is described as GTP binding; Located in intracellular, chloroplast; Contains the following InterPro domains: GTP1/OBG (InterPro:IPR006073), GTP-binding protein, HflX (InterPro:IPR016496), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: GTP-binding protein, HflX (TAIR:AT5G57960.1); Has 11258 Blast hits to 11241 proteins in 2608 species: Archae - 167; Bacteria - 7727; Metazoa - 332; Fungi - 38; Plants - 97; Viruses - 17; Other Eukaryotes - 2880 (source: NCBI BLink) (620 aa)    
Predicted Functional Partners:
PRPL35
50S ribosomal protein L35, chloroplastic; Ribosomal protein L35; Its function is described as structural constituent of ribosome; Involved in translation; Located in ribosome, chloroplast; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Ribosomal protein L35, conserved site (InterPro:IPR018265), Ribosomal protein L35, non-mitochondrial (InterPro:IPR001706), Ribosomal protein L35 (InterPro:IPR021137); Has 5391 Blast hits to 5391 proteins in 1946 species: Archae - 0; Bacteria - 4062; Metazoa - 6; Fungi - 2; Plants - 66; Viruse [...]
   
   0.716
RPL21C
50S ribosomal protein L21, chloroplastic; This protein binds to 23S ribosomal RNA in the presence of protein L20
   
 
 0.683
NFD1
50S ribosomal protein L21, mitochondrial; Encodes a ribosomal RPL21M protein that is localized to the mitochondrion and is involved in karyogamy during female gametophyte development and fertilization. Mutants display defects in both male and female gametophyte development (i.e.collapsed pollen and female gametophytes with unfused central cells)
   
 
 0.683
RPL9
50S ribosomal protein L9, chloroplastic; Plastid ribosomal protein CL9
  
   0.650
AT5G53070
Ribosomal protein L9/RNase H1; Its function is described as structural constituent of ribosome; Involved in translation, ribosome biogenesis; Located in ribosome, intracellular; Expressed in 19 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Ribosomal protein L9 (InterPro:IPR000244), Ribosomal protein L9/RNase H1, N-terminal (InterPro:IPR009027), Ribosomal protein L9, N-terminal (InterPro:IPR020070), Ribosomal protein L9, C-terminal (InterPro:IPR020069); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa [...]
  
   0.650
AT2G43030
50S ribosomal protein L3-1, chloroplastic; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
   
 
 0.602
RPL3P
50S ribosomal protein L3-2, chloroplastic; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
   
 
 0.602
AT5G63290
Oxygen-independent coproporphyrinogen-like protein; Radical SAM superfamily protein; Its function is described as oxidoreductase activity, iron-sulfur cluster binding, coproporphyrinogen oxidase activity, catalytic activity; Involved in oxidation reduction, porphyrin biosynthetic process; Located in chloroplast, cytoplasm; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Putative oxygen-independent coproporphyrinogen III oxidase (InterPro:IPR004559), HemN, C-terminal (InterP [...]
  
  
 0.600
EMB2207
Encodes a cytoplasmic ribosomal protein; Belongs to the universal ribosomal protein uL3 family
    
 
 0.599
RPL3B
60S ribosomal protein L3-2; R-protein L3 B (RPL3B); Its function is described as structural constituent of ribosome; Involved in translation; Located in ribosome, cytosolic large ribosomal subunit, membrane; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Ribosomal protein L3 (InterPro:IPR000597), Ribosomal protein L3, conserved site (InterPro:IPR019926), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: ribosomal protein 1 (TAIR:AT1G43170.8); Ha [...]
    
 
 0.599
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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