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SMC2 protein (Arabidopsis thaliana) - STRING interaction network
"SMC2" - Structural maintenance of chromosomes protein 2-1 in Arabidopsis thaliana
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second shell of interactors
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Predicted Interactions
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textmining
co-expression
protein homology
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SMC2Structural maintenance of chromosomes protein 2-1; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis (1175 aa)    
Predicted Functional Partners:
EMB2795
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). Essential protein (671 aa)
     
  0.999
HEB2
Condensin-2 complex subunit H2; Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (By similarity). The condensin-2 complex plays a role in DNA damage repair or in protecting the genome from certain genotoxic stressors (e.g. boron excess, zeocin and aphidicolin); Belongs to the CND2 H2 (condensin-2 subunit 2) family (683 aa)
     
  0.999
AT3G57060
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (1415 aa)
     
  0.999
EMB2656
ARM repeat superfamily protein; EMBRYO DEFECTIVE 2656 (EMB2656); Its function is described as binding; Involved in mitotic chromosome condensation, embryo development ending in seed dormancy; Located in cellular_component unknown; Expressed in 11 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Armadillo-type fold (InterPro-IPR016024); Has 333 Blast hits to 316 proteins in 147 species- Archae - 0; Bacteria - 4; Metazoa - 113; Fungi - 138; Plants - 47; Viruses - 0; Other Eukaryotes - 31 (source- NCBI BLink) (1051 aa)
     
  0.999
SMC3
Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Also involved in chromosome segregation in meiosis; Belongs to the SMC family. SMC4 subfamily (1244 aa)
   
0.999
HEB1
ARM repeat superfamily protein; Its function is described as binding; Located in mitochondrion; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Armadillo-type fold (InterPro-IPR016024); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (1203 aa)
     
  0.998
AT4G15890
Uncharacterized protein AT4g15890; Binding; Its function is described as binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Chromosome condensation protein, HCP-6-related (InterPro-IPR012371), Armadillo-type fold (InterPro-IPR016024); BEST Arabidopsis thaliana protein match is- binding (TAIR-AT3G57060.1); Has 443 Blast hits to 428 proteins in 158 species- Archae - 0; Bacteria - 0; Metazoa - 188; Fungi - 128; Plants - 61; Viruses - 3; Other E [...] (1314 aa)
     
  0.998
SCC3
Sister-chromatid cohesion protein 3; Essential component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Required for centromere cohesion maintenance at anaphase I and for the monopolar orientation of the kinetochores during both male and [...] (1098 aa)
     
 
  0.995
AT3G28925
BEST Arabidopsis thaliana protein match is- structural maintenance of chromosome 3 (TAIR-AT5G48600.2); Has 67 Blast hits to 50 proteins in 21 species- Archae - 0; Bacteria - 0; Metazoa - 13; Fungi - 0; Plants - 33; Viruses - 0; Other Eukaryotes - 21 (source- NCBI BLink) (247 aa)
     
 
  0.993
RBR1
Retinoblastoma-related protein 1; Key regulator of entry into cell division. Acts as a transcription repressor of E2F target genes, whose activity is required for progress from the G1 to the S phase of the cell cycle. Hyperphosphorylation by CDKA-1 prevents the binding to E2F transcription factors, allowing G1 to S phase transition to operate. Forms a stable complex with E2FA that functions in maintaining cell proliferation through repression of cell differentiation. Plays a central role in the mechanism controlling meristem cell differentiation, cell fate establishment and cell fate m [...] (1013 aa)
     
  0.990
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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