STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F20L16.80Disease resistance protein (TIR-NBS-LRR class) family. (900 aa)    
Predicted Functional Partners:
MSN2.3
Calcium uniporter protein 3, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Belongs to the MCU (TC 1.A.77) family.
   
  
 0.571
SYD
Chromatin structure-remodeling complex protein SYD; Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule d [...]
    
 0.529
ATL27
NEP1-interacting protein-like 1; May be involved in the early steps of the plant defense signaling pathway; Belongs to the RING-type zinc finger family. NIP subfamily.
   
 
 0.495
CAD1
MACPF domain-containing protein CAD1; Negatively controls the salicylic acid (SA)-mediated pathway of programmed cell death in plant immunity.
   
 
 0.492
F8D23-2
AAA-ATPase At2g18193.
   
  
 0.483
RBL-2
Protein RBL; Promotes the expression of FLC and FLC homologs to repress the floral transition. Promotes WRKY70 and LTP7 genes epigenetic methylation (e.g. H3K4me3) and subsequent expression.
    
 0.470
TRO
Protein TRAUCO; Trithorax-group gene homolog required for early embryogenesis. Required for the expression of FLC and FLC homologs and represses flowering. Required for proper leaf growth and development. Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 'Lys-4'. Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene. Involved in the transition from transcription initiation to transcription elongation.
    
 0.464
IQM4
IQ domain-containing protein IQM4; May be involved in biotic and abiotic stress responses.
   
 0.461
FLZ3
FCS-Like Zinc finger 3; May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway. Belongs to the FLZ family.
      
 0.456
SUVR5
Histone-lysine N-methyltransferase SUVR5; Histone methyltransferase that functions together with its binding partner LDL1/SWP1 as one of the regulators of flower timing in Arabidopsis. Mediates H3K9me2 deposition and regulates gene expression in a DNA methylation-independent manner. Binds DNA through its zinc fingers and represses the expression of a subset of stimulus response genes. May represent a novel mechanism for plants to regulate their chromatin and transcriptional state, which may allow for the adaptability and modulation necessary to rapidly respond to environment or develop [...]
   
 0.429
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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