node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EMB3147 | F13M22.4 | Q8RU07 | O80924 | Putative malonyl-CoA:Acyl carrier protein transacylase. | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.445 |
EMB3147 | F14A1.10 | Q8RU07 | F4K1G2 | Putative malonyl-CoA:Acyl carrier protein transacylase. | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.594 |
EMB3147 | F2G1.18 | Q8RU07 | Q9SIK4 | Putative malonyl-CoA:Acyl carrier protein transacylase. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.588 |
EMB3147 | THY-1 | Q8RU07 | Q05762 | Putative malonyl-CoA:Acyl carrier protein transacylase. | Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP. | 0.595 |
EMB3147 | THY-2 | Q8RU07 | Q05763 | Putative malonyl-CoA:Acyl carrier protein transacylase. | Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family. | 0.588 |
F13M22.4 | EMB3147 | O80924 | Q8RU07 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative malonyl-CoA:Acyl carrier protein transacylase. | 0.445 |
F13M22.4 | F14A1.10 | O80924 | F4K1G2 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.424 |
F13M22.4 | F2G1.18 | O80924 | Q9SIK4 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.496 |
F13M22.4 | NIC4_ARATH | O80924 | Q93Z51 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Probable inactive nicotinamidase At3g16190; Does not possess nicotinamidase activity in vitro. | 0.406 |
F13M22.4 | THY-1 | O80924 | Q05762 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP. | 0.496 |
F13M22.4 | THY-2 | O80924 | Q05763 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family. | 0.496 |
F13M22.4 | XK2 | O80924 | Q949W8 | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Xylulose kinase 2; Mediates 1-deoxy-D-xylulose (DX) phosphorylation in the cytoplasm prior to the translocation of 1-deoxy-D-xylulose 5-phosphate into plastids. Can also phosphorylates D-xylulose (Xyl). Uses preferentially ATP as cosubstrate; Belongs to the FGGY kinase family. | 0.412 |
F14A1.10 | EMB3147 | F4K1G2 | Q8RU07 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative malonyl-CoA:Acyl carrier protein transacylase. | 0.594 |
F14A1.10 | F13M22.4 | F4K1G2 | O80924 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.424 |
F14A1.10 | F2G1.18 | F4K1G2 | Q9SIK4 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.476 |
F14A1.10 | NIC4_ARATH | F4K1G2 | Q93Z51 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | Probable inactive nicotinamidase At3g16190; Does not possess nicotinamidase activity in vitro. | 0.553 |
F14A1.10 | THY-1 | F4K1G2 | Q05762 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP. | 0.476 |
F14A1.10 | THY-2 | F4K1G2 | Q05763 | Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. | Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family. | 0.476 |
F2G1.18 | EMB3147 | Q9SIK4 | Q8RU07 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Putative malonyl-CoA:Acyl carrier protein transacylase. | 0.588 |
F2G1.18 | F13M22.4 | Q9SIK4 | O80924 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | NAD(P)-binding Rossmann-fold superfamily protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.496 |