STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AHA1ATPase 1, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Forms a functional cation- translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (949 aa)    
Predicted Functional Partners:
PSKR1
Phytosulfokine receptor 1; Phytosulfokine receptor with both a serine/threonine-protein kinase activity and a guanylate cyclase activity. Regulates, in response to phytosulfokine binding, a signaling cascade involved in plant cell differentiation, organogenesis, somatic embryogenesis, cellular proliferation and plant growth. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Not involved in PSY perception. CNGC17 and AHAs form a functional cation-translocating unit that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes.
    
 
 0.961
CNGC17
Cyclic nucleotide-gated ion channel 17; Probable cyclic nucleotide-gated ion channel. Forms a functional cation-translocating unit with AHAs that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. Required for PSK-induced protoplast expansion.
    
 
 0.942
PSKR2
Phytosulfokine receptor 2; Phytosulfokine receptor with a serine/threonine-protein kinase activity.
   
  
 0.861
RIN4
RPM1-interacting protein 4; Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its associ [...]
    
 
 0.856
PATROL1
Protein unc-13 homolog; Controls the tethering of the proton ATPase AHA1 to the plasma membrane. Is essential for stomatal opening in response to low concentration of carbon dioxide and light. Belongs to the unc-13 family.
    
 
 0.795
PPI1
Proton pump-interactor 1; Promotes AHA1 plasma membrane ATPase activity by binding to a site different from the 14-3-3 binding site.
   
 
 0.782
PPI3B
Proton pump-interactor 3B; May regulate plasma membrane ATPase activity; Belongs to the plant Proton pump-interactor protein family.
      
 0.778
PPI4
Proton pump-interactor 4; May regulate plasma membrane ATPase activity; Belongs to the plant Proton pump-interactor protein family.
      
 0.778
PSY1R
Tyrosine-sulfated glycopeptide receptor 1; Tyrosine-sulfated glycopeptide receptor with a serine/threonine-protein kinase activity. Regulates, in response to tyrosine-sulfated glycopeptide binding, a signaling cascade involved in cellular proliferation and plant growth. Not involved in PSK perception. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Mediates activation of the plasma membrane H(+)- ATPase by PSY1. Phosphorylates AHA2 at Thr-881.
   
  
 0.772
PPA5
Soluble inorganic pyrophosphatase 5.
     
 0.766
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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