STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ASA1Anthranilate synthase alpha subunit 1, chloroplastic; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosynthet [...] (595 aa)    
Predicted Functional Partners:
ASB1
Anthranilate synthase beta subunit 1, chloroplastic; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosyntheti [...]
 0.999
PAT1
Anthranilate phosphoribosyltransferase, chloroplastic.
 0.998
ASB2
Anthranilate synthase beta subunit 2, chloroplastic; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate (By similarity).
 0.997
F4F7.41
Glutamine amidotransferase type 1 family protein.
 0.996
F5A9.17
Glutamine amidotransferase type 1 family protein.
 0.995
IGPS
Indole-3-glycerol phosphate synthase, chloroplastic; Indole-3-glycerol phosphate synthase required for tryptophan biosynthesis.
 
 0.994
MIF21.11
Aldolase-type TIM barrel family protein.
 
 0.988
EMB1144
Chorismate synthase, chloroplastic; Catalyzes the last common step of the biosynthesis of aromatic amino acids, produced via the shikimic acid pathway.
  
 
 0.977
F24J13.14
Anthranilate phosphoribosyltransferase.
  
 0.950
TSA1-2
Tryptophan synthase alpha chain, chloroplastic; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Required for tryptophan biosynthesis. Contributes to the tryptophan- independent indole biosynthesis, and possibly to auxin production. Belongs to the TrpA family.
 
  
 0.944
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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