STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP18-4Peptidyl-prolyl cis-trans isomerase CYP18-4; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (172 aa)    
Predicted Functional Partners:
MLE2.7
UPF0235 protein At5g63440; May play a role during early embryonic development. Probably involved in pre-mRNA splicing (By similarity); Belongs to the UPF0235 family.
    
  0.957
RD21A
Cysteine proteinase RD21A; Cysteine protease that plays a role in immunity, senescence, and biotic and abiotic stresses (Probable). Involved in immunity against the necrotrophic fungal pathogen Botrytis cinerea. Involved in elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions as PCD-promoting protease that is released from the ER body or vacuole to the cytoplasm. Accumulates in endoplasmic reticulum-derived bodies in epidermal cells and may participate in cell death in stressed or injured cells. Involved in wa [...]
    
 
 0.830
T19E23.9
TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein.
      
 0.784
RD21B
Probable cysteine protease RD21B; Probable thiol protease.
   
 
 0.779
XBCP3
Papain-like cysteine peptidase XBCP3; Belongs to the peptidase C1 family.
    
 
 0.772
RD21C
Probable cysteine protease RD21C; Probable thiol protease; Belongs to the peptidase C1 family.
    
 
 0.772
RPL8C
60S ribosomal protein L8-3; Belongs to the universal ribosomal protein uL2 family.
   
 
 0.744
F12A24.4
GCIP-interacting family protein.
 
  
 0.739
T32B20.g
Tetratricopeptide repeat (TPR)-like superfamily protein.
    
 0.734
SRL1
Pre-mRNA splicing factor SR-like 1; May be required for pre-mRNA splicing (Probable). Confers salt tolerance to LiCl and NaCl.
   
 
 0.709
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]