STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFGHS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)    
Predicted Functional Partners:
ADH2
Alcohol dehydrogenase class-3; Plays a central role in formaldehyde detoxification. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.983
F6N18.16
Alcohol dehydrogenase-like 3.
 0.954
F13O11.3
Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.942
CXE5
Probable carboxylesterase 5; Carboxylesterase acting on esters with varying acyl chain length.
  
  
 0.938
ADH1
Alcohol dehydrogenase class-P; Alcohol dehydrogenase mostly active on ethanol (EtOH), but exhibits broad substrates selectivity for primary and secondary alcohols (e.g. butanol, propyl alcohol, pentanol, isopentanol, ethylene glycol, isopropanol, methanol and tertiary butyl alcohol). Converts allyl alcohol to highly toxic acryl- aldehyde. Required for survival and acclimation in hypoxic conditions, especially in roots.
 0.933
K5J14.5
Alcohol dehydrogenase-like 7.
 0.933
F12K8.22
Alcohol dehydrogenase-like 1.
 0.930
T4C12_30
Alcohol dehydrogenase-like 6.
 0.927
F12K8.21
Alcohol dehydrogenase-like 2.
 0.916
F1N20.210
Alcohol dehydrogenase-like 5.
 0.914
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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