STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MHF15.11NC domain-containing protein-like protein. (259 aa)    
Predicted Functional Partners:
F28B23.26
TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein.
      
 0.927
F28B23.9
Proline-rich extensin-like family protein.
    
 0.905
HSP70-17
Heat shock 70 kDa protein 17.
   
 0.814
ACBP1
Acyl-CoA-binding domain-containing protein 1; Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA. Confers tolerance and binds to lead ions Pb(2+), probably by promoting lead translocation from roots to shoots. May function as an intracellular carrier of acyl-CoA esters (By similarity).
    
 
 0.793
A0A1P8AXB7
Acyl-CoA-binding domain protein.
      
 0.790
ABCG36
ABC transporter G family member 36; Key factor that controls the extent of cell death in the defense response. Necessary for both callose deposition and glucosinolate activation in response to pathogens. Required for limiting invasion by nonadapted powdery mildews. Confers resistance to cadmium (Cd) and lead (Pb), probably as an efflux pump of Cd2+ or Cd conjugates, and possibly, of chemicals that mediate pathogen resistance.
   
 
 0.787
HSCB
Iron-sulfur cluster co-chaperone protein HscB homolog; Co-chaperone required for the assembly of iron-sulfur [Fe-S] clusters in both mitochondria and cytosol. Required for the activity of iron-sulfur proteins such as aconitase and succinate dehydrogenase. Involved in iron homeostasis and may take part in the control of iron translocation from roots to shoots ; Belongs to the HscB family.
  
 0.785
ABCB25
ABC transporter B family member 25, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not required for mitochondrial and plastid Fe-S enzymes. Probably involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol. Mediates glutathione-dependent resistance to heavy metals such as cadmium and lead, as well as their transport from roots to leaves. Regulates nonprotein thiols (NPSH) and the cellular l [...]
      
 0.754
GR1-2
Glutathione reductase, cytosolic; Maintains high levels of reduced glutathione in the cytosol.
   
 
 0.748
TPR10
Ankyrin repeat family protein.
  
 0.742
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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