STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CESA6Cellulose synthase A catalytic subunit 6 [UDP-forming]; Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation. The presence of each protein CESA1 and CESA6 is critical for cell expansion. The hypocotyl elongation is based on a CESA6-dependent cell elongation in dark and a CESA6-independent cell elongation in light. The transition between these two mechanisms requires photosynthesis and PHYB, but not CRY1. The CESA6-depend [...] (1084 aa)    
Predicted Functional Partners:
CSI1
Protein CELLULOSE SYNTHASE INTERACTIVE 1; Regulator of the microtubular cytoskeleton. Microtubule-associated protein essential for the functional association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules. Promotes dynamics of CSCs in the plasma membrane. Regulates primary cell wall biosynthesis and cellulose microfibrils organization. Required for the regulation of root cell elongation/expansion. Necessary for the formation of ovules, pollen cell wall morphogenesis and pollen tube development. Involved in anther dehiscence, via dehydration-induced microtubule [...]
   
 0.996
CESA3
Cellulose synthase A catalytic subunit 3 [UDP-forming]; Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation, especially in roots. Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
  
 
0.993
CESA1
Cellulose synthase A catalytic subunit 1 [UDP-forming]; Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation. Required during embryogenesis for cell elongation, orientation of cell expansion and complex cell wall formations, such as interdigitated pattern of epidermal pavement cells, stomatal guard cells and trichomes. Plays a role in lateral roots formation, but seems not necessary for the development of tip-growing cel [...]
  
 
0.989
CSI3
Protein CELLULOSE SYNTHASE INTERACTIVE 3; Regulator of the microtubular cytoskeleton (By similarity). Microtubule-associated protein involved in the association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules. Promotes dynamics of CSCs in the plasma membrane in both microtubules-dependent and microtubules-independent manners. Regulates primary cell wall biosynthesis and cellulose microfibrils organization.
    
 0.953
TED6
Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 6; Involved in the secondary cell wall (SCW) formation of vessel elements (e.g. protoxylem and metaxylem), thus promoting tracheary element (TE) differentiation.
    
 0.922
CESA7
Cellulose synthase A catalytic subunit 7 [UDP-forming]; Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the secondary cell wall formation. Required for the xylem cell wall thickening. Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
  
0.912
KOR
Endoglucanase 25; Required for cellulose microfibrils formation. Involved in cell wall assembly during cell elongation and cell plate maturation in cytokinesis. Required for secondary cell wall formation in the developing xylem. May cycle through different intracellular compartments, including plasma membrane.
   
 0.885
THE1
Receptor-like protein kinase THESEUS 1; Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid-(BR-) independent manner. Mediates the response of growing plant cells to the perturbation of cellulose synthesis and may act as a cell-wall- integrity sensor. Controls ectopic-lignin accumulation in cellulose- deficient mutant backgrounds.
   
 0.820
TUBA5
Tubulin alpha-5 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
   
 0.808
CSLA7
Glucomannan 4-beta-mannosyltransferase 7; Probable mannan synthase which consists of a 4-beta- mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4- mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase. Galactomannan is a noncellulosic polysaccharides of plant cell wall. Required for synthesis of a cell wall polysaccharide essential for pollen tube growth, for cell wall structure, or for signaling during plant embryo development.
   
  
 0.805
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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