node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DCI1 | ECH2 | Q9FHR8 | Q8VYI3 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | 0.741 |
DCI1 | GPDHC1 | Q9FHR8 | O22216 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic; Involved in cell redox homeostasis. Required for maintaining a steady state cellular NADH/NAD(+) ratio through a mitochondrial glycerol-3-phosphate redox shuttle. May function with the mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase SDP6 to shuttle reducing equivalents into the mitochondria for respiration. | 0.746 |
DCI1 | LTA2 | Q9FHR8 | Q9SQI8 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.716 |
DCI1 | PEX10 | Q9FHR8 | Q9SYU4 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Peroxisome biogenesis factor 10; Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. Belongs to the pex2/pex10/pex12 family. | 0.840 |
DCI1 | PEX12 | Q9FHR8 | Q9M841 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Peroxisome biogenesis protein 12; Required for peroxisome biogenesis and for PTS1- and PTS2- dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5. | 0.816 |
DCI1 | PEX14 | Q9FHR8 | Q9FXT6 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Peroxisomal membrane protein PEX14; Controls intracellular transport of both PTS1- and PTS2- containing proteins. Required for the proper targeting of PEX7 to the peroxisome. | 0.746 |
DCI1 | PEX5 | Q9FHR8 | Q9FMA3 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Peroxisome biogenesis protein 5; Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins. | 0.942 |
DCI1 | Q9FJI2_ARATH | Q9FHR8 | Q9FJI2 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Hydroxyacyl-thioester dehydratase type-like protein. | 0.730 |
DCI1 | SCP2 | Q9FHR8 | Q9FMN0 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Sterol carrier protein 2; Enhances the transfer of lipids between membranes in vitro. Active on phosphatidylcholine (PC), 1-palmitoyl 2- oleoyl phosphatidylcholine (POPC) and ergosterol, and, to a lower extent, dimyristoyl phosphatidic acid, stigmasterol, desmosterol, beta- sitosterol and steryl glucoside. Inactive or poorly active on palmitic acid, stearoyl-coenzyme A, cholesterol, glucosylceramide and ceramide. Required during seeds and seedlings development. | 0.734 |
DCI1 | T1A4.20 | Q9FHR8 | A0A1P8BAJ1 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | Alpha/beta-Hydrolases superfamily protein. | 0.795 |
ECH2 | DCI1 | Q8VYI3 | Q9FHR8 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | 0.741 |
ECH2 | LTA2 | Q8VYI3 | Q9SQI8 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.656 |
ECH2 | PEX10 | Q8VYI3 | Q9SYU4 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Peroxisome biogenesis factor 10; Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. Belongs to the pex2/pex10/pex12 family. | 0.693 |
ECH2 | PEX12 | Q8VYI3 | Q9M841 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Peroxisome biogenesis protein 12; Required for peroxisome biogenesis and for PTS1- and PTS2- dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5. | 0.702 |
ECH2 | PEX14 | Q8VYI3 | Q9FXT6 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Peroxisomal membrane protein PEX14; Controls intracellular transport of both PTS1- and PTS2- containing proteins. Required for the proper targeting of PEX7 to the peroxisome. | 0.611 |
ECH2 | PEX5 | Q8VYI3 | Q9FMA3 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Peroxisome biogenesis protein 5; Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins. | 0.947 |
ECH2 | SCP2 | Q8VYI3 | Q9FMN0 | Enoyl-CoA hydratase 2, peroxisomal; Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids. Devoid of 3- hydroxyacyl-CoA dehydrogenase activity. | Sterol carrier protein 2; Enhances the transfer of lipids between membranes in vitro. Active on phosphatidylcholine (PC), 1-palmitoyl 2- oleoyl phosphatidylcholine (POPC) and ergosterol, and, to a lower extent, dimyristoyl phosphatidic acid, stigmasterol, desmosterol, beta- sitosterol and steryl glucoside. Inactive or poorly active on palmitic acid, stearoyl-coenzyme A, cholesterol, glucosylceramide and ceramide. Required during seeds and seedlings development. | 0.728 |
GPDHC1 | DCI1 | O22216 | Q9FHR8 | Glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic; Involved in cell redox homeostasis. Required for maintaining a steady state cellular NADH/NAD(+) ratio through a mitochondrial glycerol-3-phosphate redox shuttle. May function with the mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase SDP6 to shuttle reducing equivalents into the mitochondria for respiration. | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, peroxisomal; Converts 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl- CoAs. Involved in degradation of unsaturated fatty acids. | 0.746 |
GPDHC1 | LTA2 | O22216 | Q9SQI8 | Glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic; Involved in cell redox homeostasis. Required for maintaining a steady state cellular NADH/NAD(+) ratio through a mitochondrial glycerol-3-phosphate redox shuttle. May function with the mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase SDP6 to shuttle reducing equivalents into the mitochondria for respiration. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.527 |
GPDHC1 | T1A4.20 | O22216 | A0A1P8BAJ1 | Glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic; Involved in cell redox homeostasis. Required for maintaining a steady state cellular NADH/NAD(+) ratio through a mitochondrial glycerol-3-phosphate redox shuttle. May function with the mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase SDP6 to shuttle reducing equivalents into the mitochondria for respiration. | Alpha/beta-Hydrolases superfamily protein. | 0.754 |