STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRA19.6GDSL esterase/lipase At5g45670. (362 aa)    
Predicted Functional Partners:
Q0WPS6_ARATH
Adenine phosphoribosyltransferase.
 
    
 0.926
SAUR67
Auxin-responsive protein SAUR67; May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals. Belongs to the ARG7 family.
   
  
 0.762
GEM
GLABRA2 expression modulator; Involved in the spatial control of cell division, patterning and differentiation of Arabidopsis root epidermal cells. Could be part of a complex that negatively modulates GLABRA2 and CAPRICE expression via the maintenance of a repressor histone H3 epigenetics status of the GL2 and CPC promoters.
      
 0.739
Q9LDF5_ARATH
3-hydroxybutyryl-CoA dehydrogenase-like protein.
      
 0.720
BIM3
Transcription factor BIM3; Positive brassinosteroid-signaling protein.
      
 0.699
PAR2
Transcription factor PAR2; Atypical bHLH transcription factor that acts as negative regulator of a variety of shade avoidance syndrome (SAS) responses, including seedling elongation and photosynthetic pigment accumulation. Acts as direct transcriptional repressor of two auxin-responsive genes, SAUR15 and SAUR68. May function in integrating shade and hormone transcriptional networks in response to light and auxin changes.
   
  
 0.689
ECI2
Enoyl-CoA delta isomerase 2, peroxisomal; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids. Involved with IBR1 and IBR3 in the peroxisomal beta-oxidation of indole-3- butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin.
    
 0.619
VPS29
Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Required for the auxin-carrier protein PIN2 sorting to the lytic vacuolar pathway and the PIN1 recycling to the plasma membrane. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane.
      
 0.597
BIM2
Transcription factor BIM2; Positive brassinosteroid-signaling protein.
      
 0.541
PAH1
Phosphatidate phosphatase PAH1; Magnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH2 to repress phospholipid biosynthesis at the endoplasmic reticulum (ER). May function indirectly as repressor of multiple enzymes involved in phospholipid biosynthesis. Is involved in the pathway of galactolipid synthesis in the ER, which is required for the membrane lipid remodeling, an essential adaptation mechanism to cope with phosphate starvation; Belongs to the lipin family.
      
 0.540
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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