STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PEX1-2Pollen-specific leucine-rich repeat extensin-like protein 1; Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization. (956 aa)    
Predicted Functional Partners:
PEX6
Peroxisome biogenesis protein 6; Involved in peroxisomal-targeting signal one (PTS1) and peroxisomal-targeting signal two (PTS2) protein import. Required for jasmonate biosynthesis. Necessary for the developmental elimination of obsolete peroxisome matix proteins. May form heteromeric AAA ATPase complexes required for the import of proteins. May be involved in PEX5 recycling.
    
 
 0.986
RALFL4
Protein RALF-like 4; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
   
 
 0.979
PEX10
Peroxisome biogenesis factor 10; Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. Belongs to the pex2/pex10/pex12 family.
      
 0.964
APEM9
Protein APEM9; Involved in peroxisome biogenesis and matrix protein import. Required for pollen maturation and in vivo germination via its role in peroxisomal function, which partially involves jasmonic acid biosynthesis. Transported to peroxisomes via the interaction with PEX19-1. Required for peroxisomal protein import by acting as an anchoring protein for the AAA ATPase complex, which consists of PEX1 and PEX6.
    
 0.958
PEX5
Peroxisome biogenesis protein 5; Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins.
      
 0.930
PEX7
Peroxisome biogenesis protein 7; Import receptor for peroxisomal-targeting signal two (PTS2). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Belongs to the WD repeat peroxin-7 family.
      
 0.928
PEX16
Peroxisome biogenesis protein 16; Involved in the formation of peroxisomes, lipid bodies and protein bodies.
      
 0.926
PEX13
Peroxisomal membrane protein 13; Involved in PTS1- and PTS2-dependent protein import into peroxisomes. Required for PTS1- dependent protein import into pollen peroxisomes. Acts as a docking factor on peroxisomal membranes. Required for the proper targeting of PEX7 to the peroxisome. Required for the export/release of receptors on the peroxisome membrane. Essential for pollen-tube discharge that take place only in the presence of functional peroxisomes in either the male or the female gametophyte. Belongs to the peroxin-13 family.
      
 0.926
PUP7
Probable purine permease 7.
    
 0.791
DEG15
Glyoxysomal processing protease, glyoxysomal; Trypsin-like serine endopeptidase involved in the processing of glyoxysomal higher molecular weight precursor. The dimeric form carries out the specific cleavages needed to remove PTS2-containing presequences, whereas the monomeric form degrades the removed presequences and misfolded proteins (Probable). Not required for degradation of glyoxylate cycle enzymes during seedling development.
      
 0.784
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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