STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Q9LV46_ARATHPeroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (235 aa)    
Predicted Functional Partners:
PEX5
Peroxisome biogenesis protein 5; Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1-containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins.
   
 
 0.525
PEX19-2
Peroxisome biogenesis protein 19-2; Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins. Required for proper post- translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer; Belongs to the peroxin-19 family.
   
 0.508
PEX12
Peroxisome biogenesis protein 12; Required for peroxisome biogenesis and for PTS1- and PTS2- dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5.
     
 0.506
PEX19-1
Peroxisome biogenesis protein 19-1; Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins. Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Required for transport of APEM9 to peroxisome membranes. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer ; Belongs to the peroxin-19 family.
   
 0.506
PEX10
Peroxisome biogenesis factor 10; Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. Belongs to the pex2/pex10/pex12 family.
     
 0.496
PEX16
Peroxisome biogenesis protein 16; Involved in the formation of peroxisomes, lipid bodies and protein bodies.
     
 0.472
PEX3-1
Peroxisome biogenesis protein 3-1; Involved in morphology determination of peroxisomes, but not in import of peroxisomal matrix proteins. May act as a docking factor for PEX19 and be necessary for the import of peroxisomal membrane proteins in the peroxisomes.
   
 
 0.434
PEX3-2
Peroxisome biogenesis protein 3-2; Involved in morphology determination of peroxisomes, but not in import of peroxisomal matrix proteins. May act as a docking factor for PEX19 and be necessary for the import of peroxisomal membrane proteins in the peroxisomes.
   
 
 0.434
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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