STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATL36Putative RING-H2 finger protein ATL36; Belongs to the RING-type zinc finger family. ATL subfamily. (345 aa)    
Predicted Functional Partners:
RIN3
E3 ubiquitin protein ligase RIN3; E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN2. Probably not required for RPM1 degradation during HR.
    
 
 0.578
DSK2A
Ubiquitin domain-containing protein DSK2a; Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
    
 0.558
UBC11
Ubiquitin-conjugating enzyme E2 11; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Belongs to the ubiquitin-conjugating enzyme family.
    
 0.555
RIN2
E3 ubiquitin protein ligase RIN2; E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN3. Probably not required for RPM1 degradation during HR.
    
 
 0.544
UBC4
Ubiquitin-conjugating enzyme E2 4; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
     
 0.449
ATL49
Putative RING-H2 finger protein ATL49; May be involved in female gametophyte development.
  
   
0.415
F2H15.19
RING/U-box superfamily protein.
  
     0.414
F25P22.18
Putative RING zinc finger protein; 69105-67310.
  
     0.414
ATL81
RING-H2 finger protein ATL81; Belongs to the RING-type zinc finger family. ATL subfamily.
  
   
0.404
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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