STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEN1tRNA-splicing endonuclease subunit Sen2-1; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structur [...] (237 aa)    
Predicted Functional Partners:
F11A12.6
tRNA-splicing endonuclease subunit.
    
 0.944
Q6DBN3_ARATH
tRNA-splicing endonuclease subunit.
    
 0.944
F17F16.1
P-loop containing nucleoside triphosphate hydrolases superfamily protein.
      
 0.913
F4P9.18
RNA-binding (RRM/RBD/RNP motifs) family protein.
      
 0.822
F26A9.14
Nuclear transport factor 2 (NTF2) family protein.
      
 0.822
MAA3
Probable helicase MAGATAMA 3; Probable helicase that may regulate RNA molecules involved in nucleolar organization and pollen tube guidance. Belongs to the helicase family.
      
 0.794
B3H6J5_ARATH
Pre-mRNA-splicing factor.
      
 0.792
T5E8.110
Probable gamma-secretase subunit PEN-2; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
      
 0.784
ASPG2
Protein ASPARTIC PROTEASE IN GUARD CELL 2; Aspartic protease that may be involved in drought avoidance through abscisic acid signaling; Belongs to the peptidase A1 family.
      
 0.783
T20K24.14
P-loop containing nucleoside triphosphate hydrolases superfamily protein.
      
 0.772
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (18%) [HD]