STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXE6Probable carboxylesterase 6; Carboxylesterase acting on esters with varying acyl chain length. (336 aa)    
Predicted Functional Partners:
F7K2.50
Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein.
      
 0.784
T19P19.60
ACD11 homolog protein.
   
  
 0.764
PELPK1
Protein PELPK1; Positive regulator of germination and plant growth.
   
  
 0.724
CRRSP55
Cysteine-rich repeat secretory protein 55.
   
 
 0.714
GMI1
Structural maintenance of chromosomes flexible hinge domain-containing protein GMI1; Contributes to DNA double-strand break (DSB) repair via somatic homologous recombination. Functions downstream of ATM.
      
 0.598
PGIP1
Polygalacturonase inhibitor 1; Inhibitor of fungal polygalacturonase. It is an important factor for plant resistance to phytopathogenic fungi. Belongs to the polygalacturonase-inhibiting protein family.
   
 
 0.577
ETFQO
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. May act downstream of IVD and D2HGDH in the degradation of phytol or chlorophyll during dark-induced senescence and sugar starvation. Belongs to the ETF-QO/FixC family.
      
 0.574
RPA1E
Replication protein A 70 kDa DNA-binding subunit E; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity).
      
 0.572
AFP3
Ninja-family protein AFP3; Acts as a negative regulator of abscisic acid (ABA) response and stress responses.
   
  
 0.564
DREB2E
Dehydration-responsive element-binding protein 2E; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates abscisic acid-inducible transcription. Involved in the regulation of plant development and tolerance to abiotic stresses. Belongs to the AP2/ERF transcription factor family. ERF subfamily.
   
  
 0.556
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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