STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PBL2Probable serine/threonine-protein kinase PBL2; Involved in disease resistance signaling. Contributes to pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling and defense responses downstream of FLS2. Required for the bacterial XopAC/AvrAC effector-triggered immunity (ETI) against Xanthomonas campestris ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (426 aa)    
Predicted Functional Partners:
RPP13L4
Disease resistance RPP13-like protein 4; CC-NB-LRR receptor-like protein required for recognition of the Pseudomonas syringae type III effector HopZ1a. Confers allele- specific recognition and virulence attenuation of HopZ1a. Immunity mediated by ZAR1 is independent of several genes required by other resistance protein signaling pathways such as NDR1 and RAR1. Belongs to the disease resistance NB-LRR family. RPP13 subfamily.
   
 
 0.990
F15B8.100
Protein kinase superfamily protein.
    
 
0.927
RRS1
Disease resistance protein RRS1; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. Acts also as a disease resistance protein involved in resistance to fungal and bacterial pathogens, including R.solanacearum, P.syringae pv. tomato and C.higginsianum. Heterodimerization with RPS4 is required to form a functional complex to recognize AvrRps4 and PopP2. Contributes to temperature-conditioned RPS4 auto- immunity.
   
  
 0.759
RIN4
RPM1-interacting protein 4; Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its associ [...]
   
  
 0.730
TIR
Toll/interleukin-1 receptor-like protein; Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth (By similarity).
   
  
 0.725
SAG101
Senescence-associated carboxylesterase 101; Acyl hydrolase that triggers the leaf senescence onset. Can use triolein as substrate to produce oleic acids.
   
  
 0.708
ADR1
Disease resistance protein ADR1; Disease resistance (R) protein that mediates resistance against Hyaloperonospora parasitica in a salicylic acid-dependent manner. Also mediates resistance against Erysiphe cichoracearum is both salicylic acid-dependent and partially NPR1-dependent. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
   
  
 0.669
CYP71B23
Cytochrome P450 71B23; Belongs to the cytochrome P450 family.
   
 
 0.661
RBOHD
Respiratory burst oxidase homolog protein D; Calcium-dependent NADPH oxidase that generates superoxide. Involved in the generation of reactive oxygen species (ROS) during incompatible interactions with pathogens and in UV-B and abscisic acid ROS-dependent signaling. Might be required for ROS signal amplification during light stress. Belongs to the RBOH (TC 5.B.1.3) family.
   
  
 0.643
RLP39
Receptor-like protein 39.
   
 0.631
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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