STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARD41,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (187 aa)    
Predicted Functional Partners:
K19P17.1
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1; In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily.
 
 
 0.994
ISS1
Aromatic aminotransferase ISS1; Coordinates and prevents auxin (IAA) and ethylene biosynthesis, thus regulating auxin homeostasis in young seedlings. Shows aminotransferase activity with methionine; can use the ethylene biosynthetic intermediate L- methionine (L-Met) as an amino donor and the auxin biosynthetic intermediate, indole-3-pyruvic acid (3-IPA) as an amino acceptor to produce L-tryptophan (L-Trp) and 2-oxo-4-methylthiobutyric acid (KMBA). Can also use tryptophan (Trp), phenylalanine (Phe), and tyrosine (Tyr) as substrates. Regulates tryptophan (Trp) homeostasis and catabolism [...]
  
 
 0.939
T5M16.26
Pyridoxal phosphate (PLP)-dependent transferases superfamily protein.
  
 
 0.939
ARD2
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
0.924
ARD3
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 3; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene); Belongs to the acireductone dioxygenase (ARD) family.
  
 
0.910
ARD1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
  
0.904
T20H2.11
DNA ligase-like protein.
      
 0.800
TAT7
Probable aminotransferase TAT2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.796
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using L-glutamate in vitro. Can convert phenylalanine to phenylpyruvate and catalyze the reverse reaction in vitro. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.796
F18O22.30
Thioredoxin superfamily protein.
      
 0.793
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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