STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
RHA2BE3 ubiquitin-protein ligase RHA2B; E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid (ABA) signaling and responses to salt and osmotic stresses during seed germination and early seedling development. Acts additively with RHA2A in regulating ABA signaling and drought response. Possesses E3 ubiquitin ligase activity in vitro. (147 aa)    
Predicted Functional Partners:
MYB30
Transcription factor MYB30; Transcription factor that binds specifically to the DNA sequence 5'-AACAAAC-3'. Acts as a positive regulator of hypersensitive cell death. Acts as a positive regulator of salicylic acid synthesis. Regulates very-long-chain fatty acid biosynthesis. Acts cooperatively with BZR2 to promote expression of a subset of brassinosteroids target genes. Transcriptional activity and hypersensitive response control negatively regulated by PLA2-ALPHA and by the Xanthomonas type III effector XopD (AC G9L9K6). Involved in the regulation of abscisic acid (ABA) signaling. Inc [...]
      
 0.884
ATL9
E3 ubiquitin-protein ligase ATL9; E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro. May be involved in the early steps of the plant defense signaling pathway.
  
   
 0.856
SDIR1
E3 ubiquitin-protein ligase SDIR1; E3 ubiquitin-protein ligase that acts as a positive regulator of abscisic acid-related stress signal transduction. Interacts with and ubiquitinates ATP1/SDIRIP1 to modulate ATP1/SDIRIP1 stability through the 26S proteasome pathway. Regulates abscisic acid (ABA) and salt stress responses by negatively affecting ATP1/SDIRIP1 stability. The SDIR1-ATP1/SDIRIP1 complex plays an important role in ABA signaling through the ubiquitination pathway.
      
 0.809
AIRP1
E3 ubiquitin-protein ligase AIRP1; Possesses E3 ubiquitin-protein ligase activity in vitro when associated with the E2 enzyme UBC8 in vitro. Plays combinatory roles with AIRP2 in the positive regulation of the abscisic acid-mediated drought stress response.
      
 0.795
MIEL1
E3 ubiquitin-protein ligase MIEL1; E3 ubiquitin-protein ligase that acts as a regulator of cell death and defense. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Attenuates the activation of defense and related cell death responses in the absence of pathogens by mediating ubiquitination and subsequent proteasomal degradation of MYB30.
     
 0.792
RIE1
E3 ubiquitin protein ligase RIE1; Probable E3 ubiquitin-protein ligase required for embryo development.
      
 0.783
PI4KG2
Phosphatidylinositol 4-kinase gamma 2; The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5- bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3); Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
    
 0.780
AIP2
E3 ubiquitin-protein ligase AIP2; E3 ubiquitin-protein ligase that acts as a negative regulator of abscisic acid (ABA) signaling. Mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ABI3.
      
 0.778
ATL56
RING-H2 finger protein ATL56; Belongs to the RING-type zinc finger family. ATL subfamily.
      
 0.776
ARI9
Probable E3 ubiquitin-protein ligase ARI9; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates; Belongs to the RBR family. Ariadne subfamily.
     
 0.762
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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