STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC1L1NPC1 like intracellular cholesterol transporter 1. (1331 aa)    
Predicted Functional Partners:
NPC2
NPC intracellular cholesterol transporter 2.
    
 0.951
SREBF2
Sterol regulatory element binding transcription factor 2.
   
 0.892
SREBF1
Sterol regulatory element binding transcription factor 1.
   
 0.872
INSIG2
Insulin induced gene 2.
   
 0.832
ENSSSUP00005016922
annotation not available
   
 0.829
ABCG5
ATP binding cassette subfamily G member 5.
   
 
 0.765
ABCG8
ATP binding cassette subfamily G member 8.
   
 
 0.731
SCARB1
Scavenger receptor class B member 1.
   
  
 0.627
OSBPL5
Oxysterol binding protein like 5.
   
 0.624
ABCB11
ATP binding cassette subfamily B member 11.
   
 
 0.557
Your Current Organism:
Suricata suricatta
NCBI taxonomy Id: 37032
Other names: S. suricatta, meerkat, slender-tailed meerkat, suricate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.