STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGFREpidermal growth factor receptor. (1202 aa)    
Predicted Functional Partners:
EGF
Epidermal growth factor.
   
 0.999
CBL
Cbl proto-oncogene.
    
 0.999
EREG
Epiregulin.
    
 0.998
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.997
TGFA
Transforming growth factor alpha.
    
 0.997
ERBB2
Erb-b2 receptor tyrosine kinase 2.
  
 
0.997
HBEGF
Heparin binding EGF like growth factor.
    
 0.996
PTK2
Protein tyrosine kinase 2.
    
0.996
ERBB3
Erb-b2 receptor tyrosine kinase 3.
  
 
0.995
AREG
Amphiregulin.
    
 0.994
Your Current Organism:
Suricata suricatta
NCBI taxonomy Id: 37032
Other names: S. suricatta, meerkat, slender-tailed meerkat, suricate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.