STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAB2GRB2 associated binding protein 2. (656 aa)    
Predicted Functional Partners:
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
     
 0.928
LYN
LYN proto-oncogene, Src family tyrosine kinase.
     
 0.917
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 
 0.914
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 
 0.914
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
     
 0.912
PLCG2
Phospholipase C gamma 2.
     
 0.912
KIT
KIT proto-oncogene, receptor tyrosine kinase.
     
 0.910
PDGFRA
Platelet derived growth factor receptor alpha.
     
 0.910
EGFR
Epidermal growth factor receptor.
     
 0.910
TRAF6
TNF receptor associated factor 6.
     
 0.910
Your Current Organism:
Suricata suricatta
NCBI taxonomy Id: 37032
Other names: S. suricatta, meerkat, slender-tailed meerkat, suricate
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.