| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Efp | PTH | PTH_1162 | PTH_0113 | Translation elongation factor P /translation initiation factor 5A; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | peptidyl-tRNA hydrolase. | 0.650 |
| Efp | RplY | PTH_1162 | PTH_0112 | Translation elongation factor P /translation initiation factor 5A; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.939 |
| Efp | guaA | PTH_1162 | PTH_2551 | Translation elongation factor P /translation initiation factor 5A; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.693 |
| MesJ | PTH | PTH_0197 | PTH_0113 | Predicted ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | peptidyl-tRNA hydrolase. | 0.785 |
| MesJ | PTH_0117 | PTH_0197 | PTH_0117 | Predicted ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Hypothetical protein; Containing SrmB, superfamily II DNA and RNA helicases (COG0513) and TRCF domain. | 0.693 |
| MesJ | QRI7 | PTH_0197 | PTH_2656 | Predicted ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Metal-dependent proteases; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.521 |
| MesJ | UvrB | PTH_0197 | PTH_0116 | Predicted ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Helicase subunit of the DNA excision repair complex. | 0.672 |
| MesJ-2 | PTH | PTH_2665 | PTH_0113 | Predicted ATPase; PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | peptidyl-tRNA hydrolase. | 0.625 |
| MesJ-2 | PTH_0117 | PTH_2665 | PTH_0117 | Predicted ATPase; PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | Hypothetical protein; Containing SrmB, superfamily II DNA and RNA helicases (COG0513) and TRCF domain. | 0.469 |
| MesJ-2 | UvrB | PTH_2665 | PTH_0116 | Predicted ATPase; PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | Helicase subunit of the DNA excision repair complex. | 0.469 |
| PTH | Efp | PTH_0113 | PTH_1162 | peptidyl-tRNA hydrolase. | Translation elongation factor P /translation initiation factor 5A; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.650 |
| PTH | MesJ | PTH_0113 | PTH_0197 | peptidyl-tRNA hydrolase. | Predicted ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.785 |
| PTH | MesJ-2 | PTH_0113 | PTH_2665 | peptidyl-tRNA hydrolase. | Predicted ATPase; PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | 0.625 |
| PTH | PTH_0114 | PTH_0113 | PTH_0114 | peptidyl-tRNA hydrolase. | Hypothetical membrane protein. | 0.694 |
| PTH | PTH_0117 | PTH_0113 | PTH_0117 | peptidyl-tRNA hydrolase. | Hypothetical protein; Containing SrmB, superfamily II DNA and RNA helicases (COG0513) and TRCF domain. | 0.680 |
| PTH | QRI7 | PTH_0113 | PTH_2656 | peptidyl-tRNA hydrolase. | Metal-dependent proteases; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.633 |
| PTH | RplY | PTH_0113 | PTH_0112 | peptidyl-tRNA hydrolase. | Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.856 |
| PTH | UvrB | PTH_0113 | PTH_0116 | peptidyl-tRNA hydrolase. | Helicase subunit of the DNA excision repair complex. | 0.731 |
| PTH | guaA | PTH_0113 | PTH_2551 | peptidyl-tRNA hydrolase. | Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.654 |
| PTH | ychF | PTH_0113 | PTH_0927 | peptidyl-tRNA hydrolase. | Predicted GTPase, probable translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.851 |