Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_0125Hypothetical membrane protein. (190 aa)    
Predicted Functional Partners:
PTH_0124
Hypothetical protein.
 
  
 0.972
PTH_1957
Hypothetical protein.
  
     0.755
PTH_0889
Hypothetical membrane protein; Containing Yqf domain.
  
   
 0.741
PTH_0122
Ribosome-associated heat shock protein; Implicated in the recycling of the 50S subunit (S4 paralog).
  
    0.709
PTH_1847
peptidase_U4, Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.626
PTH_1173
Hypothetical protein.
  
     0.610
HimA
Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
  
    0.588
PTH_0054
Hypothetical membrane protein.
  
   
 0.567
PTH_0562
Hypothetical membrane protein.
  
     0.558
PTH_1642
Hypothetical membrane protein; Containing GIDA domain.
  
    0.512
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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