| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BirA | NadB | PTH_0255 | PTH_0223 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.639 |
| BirA | PTH_0219 | PTH_0255 | PTH_0219 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Uncharacterized conserved protein. | 0.408 |
| BirA | PanB | PTH_0255 | PTH_0220 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.718 |
| BirA | PanC | PTH_0255 | PTH_0221 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.705 |
| BirA | PanD | PTH_0255 | PTH_0222 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.655 |
| NadB | BirA | PTH_0223 | PTH_0255 | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.639 |
| NadB | PTH_0219 | PTH_0223 | PTH_0219 | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Uncharacterized conserved protein. | 0.409 |
| NadB | PanB | PTH_0223 | PTH_0220 | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.407 |
| NadB | PanC | PTH_0223 | PTH_0221 | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.662 |
| NadB | PanD | PTH_0223 | PTH_0222 | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.908 |
| PTH_0218 | PTH_0219 | PTH_0218 | PTH_0219 | Uncharacterized conserved protein. | Uncharacterized conserved protein. | 0.401 |
| PTH_0218 | PanB | PTH_0218 | PTH_0220 | Uncharacterized conserved protein. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.401 |
| PTH_0219 | BirA | PTH_0219 | PTH_0255 | Uncharacterized conserved protein. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.408 |
| PTH_0219 | NadB | PTH_0219 | PTH_0223 | Uncharacterized conserved protein. | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.409 |
| PTH_0219 | PTH_0218 | PTH_0219 | PTH_0218 | Uncharacterized conserved protein. | Uncharacterized conserved protein. | 0.401 |
| PTH_0219 | PanB | PTH_0219 | PTH_0220 | Uncharacterized conserved protein. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.941 |
| PTH_0219 | PanC | PTH_0219 | PTH_0221 | Uncharacterized conserved protein. | Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.988 |
| PTH_0219 | PanD | PTH_0219 | PTH_0222 | Uncharacterized conserved protein. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.725 |
| PanB | BirA | PTH_0220 | PTH_0255 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.718 |
| PanB | NadB | PTH_0220 | PTH_0223 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.407 |