Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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ThiFDinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2. (271 aa)    
Predicted Functional Partners:
NifS
Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.936
NifS-2
Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.936
ThiS
Sulfur transfer protein; Involved in thiamine biosynthesis.
  
 0.926
MoaD
Molybdopterin converting factor, small subunit.
  
 0.926
ThiF-3
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
  
  
 
0.912
ThiF-2
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
  
  
 
0.902
SirA
Predicted redox protein; Regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
 
   
 0.872
PTH_0245
Hypothetical protein; Containing OmpR response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain (COG0745).
       0.773
PTH_0246
Hypothetical protein; Containing BaeS signal transduction histidine kinase (COG0642).
       0.773
MobB
Molybdopterin-guanine dinucleotide biosynthesis protein.
 
  
 0.699
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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