Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PaaKCoenzyme F390 synthetase. (468 aa)    
Predicted Functional Partners:
RfaG
Glycosyltransferase.
      0.809
PTH_0385
Hypothetical protein.
 
     0.670
CaiC-2
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
 0.621
CaiC-4
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
 0.621
PTH_1584
Putative aldehyde/alcohol dehydrogenase; Containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.577
WecB
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
       0.572
PTH_0383
Uncharacterized protein conserved in archaea.
       0.563
WecC
UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.535
PTH_0380
Carbonic anhydrases/acetyltransferases; Isoleucine patch superfamily.
       0.528
MviM
Predicted dehydrogenases and related proteins.
       0.525
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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